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Acoustical Slot Mode Sensor for the Rapid Coronaviruses Detection.
Guliy, Olga; Zaitsev, Boris; Teplykh, Andrey; Balashov, Sergey; Fomin, Alexander; Staroverov, Sergey; Borodina, Irina.
  • Guliy O; Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, Saratov 410049, Russia.
  • Zaitsev B; Kotel'nikov Institute of Radio Engineering and Electronics of RAS, Saratov Branch, Saratov 410019, Russia.
  • Teplykh A; Kotel'nikov Institute of Radio Engineering and Electronics of RAS, Saratov Branch, Saratov 410019, Russia.
  • Balashov S; Information Technology Center Renato Archer, Campinas CEP, SP 13069-901, Brazil.
  • Fomin A; Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, Saratov 410049, Russia.
  • Staroverov S; Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, Saratov 410049, Russia.
  • Borodina I; Kotel'nikov Institute of Radio Engineering and Electronics of RAS, Saratov Branch, Saratov 410019, Russia.
Sensors (Basel) ; 21(5)2021 Mar 05.
Article in English | MEDLINE | ID: covidwho-1128798
ABSTRACT
A method for the rapid detection of coronaviruses is presented on the example of the transmissible gastroenteritis virus (TGEV) directly in aqueous solutions with different conductivity. An acoustic sensor based on a slot wave in an acoustic delay line was used for the research. The addition of anti-TGEV antibodies (Abs) diluted in an aqueous solution led to a change in the depth and frequency of resonant peaks on the frequency dependence of the insertion loss of the sensor. The difference in the output parameters of the sensor before and after the biological interaction of the TGE virus in solutions with the specific antibodies allows drawing a conclusion about the presence/absence of the studied viruses in the analyzed solution. The possibility for virus detection in aqueous solutions with the conductivity of 1.9-900 µs/cm, as well as in the presence of the foreign viral particles, has been demonstrated. The analysis time did not exceed 10 min.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Coronavirus / Transmissible gastroenteritis virus Type of study: Experimental Studies Language: English Year: 2021 Document Type: Article Affiliation country: S21051822

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Coronavirus / Transmissible gastroenteritis virus Type of study: Experimental Studies Language: English Year: 2021 Document Type: Article Affiliation country: S21051822