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Regional Survey in Lombardy, Northern Italy, on Vascular Surgery Intervention Outcomes During The COVID-19 Pandemic.
Bellosta, Raffaello; Piffaretti, Gabriele; Bonardelli, Stefano; Castelli, Patrizio; Chiesa, Roberto; Frigerio, Dalmazio; Lanza, Gaetano; Pirrelli, Stefano; Rossi, Giovanni; Trimarchi, Santi.
  • Bellosta R; Vascular Surgery, Cardiovascular Department, Poliambulanza Foundation, Brescia, Italy.
  • Piffaretti G; Vascular Surgery - Department of Medicine and Surgery, University of Insubria School of Medicine, ASST Settelaghi Circolo University Teaching Hospital, via F. Guicciardini 9, 21100, Varese, Italy. Electronic address: gabriele.piffaretti@uninsubria.it.
  • Bonardelli S; Vascular Surgery, Department of Surgery, Spedali Civili University Teaching Hospital, University of Brescia School of Medicine, Brescia, Italy.
  • Castelli P; Vascular Surgery - Department of Medicine and Surgery, University of Insubria School of Medicine, ASST Settelaghi Circolo University Teaching Hospital, via F. Guicciardini 9, 21100, Varese, Italy.
  • Chiesa R; Vascular Surgery, University "Vita Salute" San Raffaele Institute, Milan, Italy.
  • Frigerio D; Vascular Surgery, ASST Vimercate, Vimercate, Italy.
  • Lanza G; Vascular Surgery, IRCCS Multimedica, Castellanza, Italy.
  • Pirrelli S; Vascular Surgery - Cardiovascular Department, ASST Papa Giovanni XXIII, Bergamo, Italy.
  • Rossi G; Vascular Surgery, Cardiovascular Department, "Alessandro Manzoni" Hospital, Lecco, Italy.
  • Trimarchi S; Vascular Surgery, Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, Milan, Italy; Department of Clinical and Community Sciences, University of Milano, Milan, Italy.
Eur J Vasc Endovasc Surg ; 61(4): 688-697, 2021 04.
Article in English | MEDLINE | ID: covidwho-1128971
ABSTRACT

OBJECTIVE:

The characteristics and outcomes of patients undergoing vascular surgery hospitalised and managed in Lombardy are described with a comparison of patients tested positive for COVID-19 (CV19-pos) vs. those tested negative (CV19-neg).

METHODS:

This was a multicentre, retrospective, observational cohort study which involved all vascular surgery services in Lombardy, Northern Italy. Data were retrospectively merged into a combined dataset covering the nine weeks of the Italian COVID-19 pandemic phase 1 (8 March 2020 to 3 May 2020). The primary outcome was freedom from in hospital death, secondary outcomes were re-thrombosis rate after peripheral revascularisation, and freedom from post-operative complication.

RESULTS:

Among 674 patients managed during the outbreak, 659 (97.8%) were included in the final

analysis:

121 (18.4%) were CV19-pos. CV19-pos status was associated with a higher rate of complications (OR 4.5; p < .001, 95% CI 2.64 - 7.84), and a higher rate of re-thrombosis after peripheral arterial revascularisation (OR 2.2; p = .004, 95% CI 1.29 - 3.88). In hospital mortality was higher in CV19-pos patients (24.8% vs. 5.6%; OR 5.4, p < .001;95% CI 2.86 - 8.92). Binary logistic regression analysis identified CV19-pos status (OR 7.6; p < .001, 95% CI 3.75 - 15.28) and age > 80 years (OR 3.2; p = .001, 95% CI 1.61 - 6.57) to be predictors of in hospital death.

CONCLUSION:

In this experience of the vascular surgery group of Lombardy, COVID-19 infection was a marker of poor outcomes in terms of mortality and post-operative complications for patients undergoing vascular surgery treatments.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Postoperative Complications / Vascular Surgical Procedures / COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study Limits: Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Journal: Eur J Vasc Endovasc Surg Journal subject: Vascular Diseases Year: 2021 Document Type: Article Affiliation country: J.ejvs.2021.01.037

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Postoperative Complications / Vascular Surgical Procedures / COVID-19 Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study Limits: Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Journal: Eur J Vasc Endovasc Surg Journal subject: Vascular Diseases Year: 2021 Document Type: Article Affiliation country: J.ejvs.2021.01.037