The evolution of chest CT findings from admission to follow-up in 30 moderate to severe adult patients with COVID-19 pneumonia.
Chin J Acad Radiol
; 4(1): 71-77, 2021.
Article
in English
| MEDLINE | ID: covidwho-1130990
ABSTRACT
OBJECTIVE:
To analyze the evolution of chest computed tomography (CT) findings from admission to follow-up in moderate to severe patients with coronavirus disease-19 (COVID-19) pneumonia.METHODS:
During December 2019-April 2020, the sequential CT images of 30 patients with COVID-19 pneumonia were retrospectively analyzed from admission to follow-up. The qualitative evolution tendency of lung abnormalities and semi-quantitative CT scores were analyzed for temporal change.RESULTS:
The mean hospitalized period was 24.5 ± 9.6 days (range 6-49 days). The average time from the first, second, third, fourth and follow-up CT examination to the initial symptom onset were 4.2 ± 3.1 days, 10.7 ± 4.4 days, 17.1 ± 3.9 days, 24.6 ± 7.5 days, and 42.4 ± 15.6 days, respectively. During illness day 0-5, groundglass opacity (GGO) was the main pattern. The following illness day 6-11, the main CT pattern was consolidation and reticular pattern. The consolidation and reticular pattern gradually dissipate during illness day 12-23, and the reticular pattern and light GGO increased. When illness day was ≥ 24 days, the reticular pattern and light GGO gradually decrease until complete dissipation. The highest CT score was at illness day 6-11. Pearson correlation analysis showed that the mean and maximum CT score were not correlated with the length of fever (r = 0.018, p = 0.923 and r = 0.086, p = 0.652) and hospitalization (r = 0.192, p = 0.31 and r = 0.273, p = 0.144).CONCLUSIONS:
The dynamic evolution of CT manifestation in moderate to severe COVID-19 pneumonia patients followed a specific pattern over time. During illness day 6-11, the extent of lung abnormalities on chest CT was the most severe. SUPPLEMENTARY INFORMATION The online version contains supplementary material available at 10.1007/s42058-021-00058-2.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Cohort study
/
Prognostic study
/
Qualitative research
Language:
English
Journal:
Chin J Acad Radiol
Year:
2021
Document Type:
Article
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