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Sensitivity of Nasopharyngeal Swabs and Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2.
Jamal, Alainna J; Mozafarihashjin, Mohammad; Coomes, Eric; Powis, Jeff; Li, Angel X; Paterson, Aimee; Anceva-Sami, Sofia; Barati, Shiva; Crowl, Gloria; Faheem, Amna; Farooqi, Lubna; Khan, Saman; Prost, Karren; Poutanen, Susan; Taylor, Maureen; Yip, Lily; Zhong, Xi Zoe; McGeer, Allison J; Mubareka, Samira.
  • Jamal AJ; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada.
  • Mozafarihashjin M; Sinai Health System, Toronto, Canada.
  • Coomes E; Faculty of Medicine, University of Toronto, Toronto, Canada.
  • Powis J; Sinai Health System, Toronto, Canada.
  • Li AX; Faculty of Medicine, University of Toronto, Toronto, Canada.
  • Paterson A; Michael Garron Hospital, Toronto, Canada.
  • Anceva-Sami S; Sinai Health System, Toronto, Canada.
  • Barati S; Sinai Health System, Toronto, Canada.
  • Crowl G; Sinai Health System, Toronto, Canada.
  • Faheem A; Sinai Health System, Toronto, Canada.
  • Farooqi L; Sinai Health System, Toronto, Canada.
  • Khan S; Sinai Health System, Toronto, Canada.
  • Prost K; Sinai Health System, Toronto, Canada.
  • Poutanen S; Sinai Health System, Toronto, Canada.
  • Taylor M; Sunnybrook Health Sciences Centre, Toronto, Canada.
  • Yip L; Sinai Health System, Toronto, Canada.
  • Zhong XZ; Faculty of Medicine, University of Toronto, Toronto, Canada.
  • McGeer AJ; Michael Garron Hospital, Toronto, Canada.
  • Mubareka S; Sunnybrook Health Sciences Centre, Toronto, Canada.
Clin Infect Dis ; 72(6): 1064-1066, 2021 03 15.
Article in English | MEDLINE | ID: covidwho-1132452
ABSTRACT
We enrolled 91 consecutive inpatients with COVID-19 at 6 hospitals in Toronto, Canada, and tested 1 nasopharyngeal swab/saliva sample pair from each patient using real-time RT-PCR for severe acute respiratory syndrome coronavirus 2. Sensitivity was 89% for nasopharyngeal swabs and 72% for saliva (P = .02). Difference in sensitivity was greatest for sample pairs collected later in illness.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Diagnostic study Limits: Humans Country/Region as subject: North America Language: English Journal: Clin Infect Dis Journal subject: Communicable Diseases Year: 2021 Document Type: Article Affiliation country: Cid

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Full text: Available Collection: International databases Database: MEDLINE Main subject: SARS-CoV-2 / COVID-19 Type of study: Diagnostic study Limits: Humans Country/Region as subject: North America Language: English Journal: Clin Infect Dis Journal subject: Communicable Diseases Year: 2021 Document Type: Article Affiliation country: Cid