Is COVID-19-Induced Platelet Activation a Cause of Concern for Patients with Cancer?
Cancer Res
; 81(5): 1209-1211, 2021 03 01.
Article
in English
| MEDLINE | ID: covidwho-1133379
ABSTRACT
Patients with cancer are more susceptible to be infected by SARS-CoV-2 and develop severe outcomes including ICU admittance, mechanical ventilator support, and a high rate of mortality. Like mid-to late-stage cancer, SARS-CoV-2 infection is associated with platelet hyperactivity, systemic inflammation, thrombotic complications, and coagulopathy. Platelets also promote cancer cell growth, survival in circulation, and angiogenesis at sites of metastases. In this article, we will discuss the potential for platelets in the development of systemic inflammation and thrombosis in SARS-CoV-2-infected patients with cancer, with the concern that the platelet-induced pathogenic events are likely magnified in cancer patients with COVID-19.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Platelet Activation
/
SARS-CoV-2
/
COVID-19
/
Neoplasms
Type of study:
Diagnostic study
/
Prognostic study
Topics:
Long Covid
Limits:
Humans
Language:
English
Journal:
Cancer Res
Year:
2021
Document Type:
Article
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