Outcomes of COVID-19 patients with comorbidities in southwest Nigeria.
PLoS One
; 16(3): e0248281, 2021.
Article
in English
| MEDLINE | ID: covidwho-1133691
ABSTRACT
BACKGROUND:
Data on the comorbidities that result in negative outcomes for people with COVID-19 are currently scarce for African populations. This study identifies comorbidities that predict death among a large sample of COVID-19 patients from Nigeria.METHODS:
This was a retrospective analysis of medical records for 2184 laboratory confirmed cases of COVID-19 in Lagos, southwest Nigeria. Extracted data included age, sex, severity of condition at presentation and self-reported comorbidities. The outcomes of interest were death or discharge from facility.RESULTS:
Most of the cases were male (65.8%) and the median age was 43 years (IQR 33-55). Four hundred and ninety-two patients (22.5%) had at least one comorbidity and the most common amongst them were hypertension (74.2%) and diabetes (30.3%). The mortality rate was 3.3% and a significantly higher proportion of patients with comorbidities died compared to those with none. The comorbidities that predicted death were hypertension (OR 2.21, 95%CI 1.22-4.01), diabetes (OR 3.69, 95% CI 1.99-6.85), renal disease (OR 12.53, 95%CI 1.97-79.56), cancer (OR 14.12, 95% CI 2.03-98.19) and HIV (OR 1.77-84.15].CONCLUSION:
Comorbidities are prevalent and the associated risk of death is high among COVID-19 patients in Lagos, Nigeria. Public enlightenment, early identification and targeted care for COVID-19 cases with comorbidities are recommended as the pandemic evolves.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Comorbidity
/
COVID-19
Type of study:
Observational study
/
Prognostic study
/
Randomized controlled trials
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Africa
Language:
English
Journal:
PLoS One
Journal subject:
Science
/
Medicine
Year:
2021
Document Type:
Article
Affiliation country:
Journal.pone.0248281
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