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Concurrent chronic lymphocytic leukemia and COVID-19: A comprehensive review of epidemiological, diagnostic, and therapeutic challenges.
Roosta, Yousef; Behzadi, Farhad; Askari, Elham; Raeisi, Mortaza; Danandeh Mehr, Amin; Nouri-Vaskeh, Masoud.
  • Roosta Y; Department of Internal Medicine, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
  • Behzadi F; Department of Internal Medicine, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
  • Askari E; Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NTITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Raeisi M; Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Danandeh Mehr A; Department of Internal Medicine, School of Medicine and Allied Sciences, Ardabil University of Medical Sciences, Ardabil, Iran.
  • Nouri-Vaskeh M; Tropical and Communicable Diseases Research Centre, Iranshahr University of Medical Sciences, Iranshahr, Iran.
Leuk Res Rep ; 15: 100239, 2021.
Article in English | MEDLINE | ID: covidwho-1135486
ABSTRACT
A comprehensive review of the literature on chronic lymphocytic leukemia (CLL) patients and recommendations regarding the evaluation and treatment of these patients was conducted. The overall prevalence of CLL and COVID-19 concurrence was found to be 0.6% (95%CI 0.5% to 0.7%). Diagnostic interaction between CLL and COVID-19 remains a major challenge. Also, CLL patients have a lower rate of anti-SARS-CoV-2 IgG development. Evidences show the unacceptable therapeutic outcome in these patients. Although the CLL-COVID-19 occurrence is associated with adverse clinical consequences, no general and standard agreement has yet been presented for the management and treatment of this disease.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Observational study / Prognostic study Language: English Journal: Leuk Res Rep Year: 2021 Document Type: Article Affiliation country: J.lrr.2021.100239

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies / Observational study / Prognostic study Language: English Journal: Leuk Res Rep Year: 2021 Document Type: Article Affiliation country: J.lrr.2021.100239