The Deadly Quartet (Covid-19, Old Age, Lung Disease, and Heart Failure) Explains Why Coronavirus-Related Mortality in Northern Italy Was So High.
Curr Cardiol Rev
; 17(1): 74-77, 2021.
Article
in English
| MEDLINE | ID: covidwho-1136353
ABSTRACT
Since its outbreak in China at the end of 2019, the new coronavirus disease (COVID-19) was characterized by both easy spreading and high mortality. The latter proved to be way more elevated in the North of Italy -with a peak of 18.4% in region Lombardia and even 31% in the city of Bergamo and surrounding county- than in the rest of the world. In an attempt to conceptualize the reasons for such a dramatic situation, four key elements have been identified COVID-19 itself, old age, lung disease, and heart failure. Their harmful combination has been named "The deadly quartet". The underlying risk factors, among which a lot of them are distinctive features of the population in northern Italy, have been summarized as "unmodifiable", "partially modifiable", and "modifiable", for the sake of clarity. Up-to-date scientific evidence in this field has been described in the form of a narrative and easy-to-read review.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
/
Heart Failure
/
Lung Diseases
Type of study:
Observational study
/
Prognostic study
Limits:
Aged
/
Humans
Country/Region as subject:
Europa
Language:
English
Journal:
Curr Cardiol Rev
Year:
2021
Document Type:
Article
Affiliation country:
1573403X16666200731162614
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