Vulnerability and Burden of All-Cause Mortality Associated with Particulate Air Pollution during COVID-19 Pandemic: A Nationwide Observed Study in Italy.
Toxics
; 9(3)2021 Mar 15.
Article
in English
| MEDLINE | ID: covidwho-1136545
ABSTRACT
BACKGROUND:
Limited evidence is available on the health effects of particulate matter (PM including PM2.5 with an aerodynamic diameter ≤ 2.5 µm; PM10, ≤ 10 µm; PM2.5-10, 2.5-10 µm) during the pandemic of COVID-19 in Italy. The aims of the study were to examine the associations between all-cause mortality and PM in the pandemic period and compare them to the normal periods (2015-2019).METHODS:
We collected daily data regarding all-cause mortality (stratified by age and gender), and PM concentrations for 107 Italian provinces from 1 January 2015 to 31 May 2020. A time-stratified case-cross design with the distributed lag non-linear model was used to examine the association between PM and all-cause mortality. We also compared the counts and fractions of death attributable to PM in two periods.RESULTS:
Italy saw an increase in daily death counts while slight decreases in PM concentrations in pandemic period. Each 10 µg/m3 increase in PM was associated with much higher increase in daily all-cause mortality during the pandemic period compared to the same months during 2015-2019 (increased mortality rate 7.24% (95%CI 4.84%, 9.70%) versus 1.69% (95%CI 1.12%, 2.25%) for PM2.5; 3.45% (95%CI 2.58%, 4.34%) versus 1.11% (95%CI 0.79%, 1.42%) for PM10; 4.25% (95%CI 2.99%, 5.52%) versus 1.76% (95%CI 1.14%, 2.38%) for PM2.5-10). The counts and fractions of deaths attributable to PM were higher in 2020 for PM2.5 (attributable death counts 20,062 versus 3927 per year in 2015-2019; attributable fractions 10.2% versus 2.4%), PM10 (15,112 versus 3999; 7.7% versus 2.5%), and PM2.5-10 (7193 versus 2303; 3.7% versus 1.4%).CONCLUSION:
COVID-19 pandemic increased the vulnerability and excess cases of all-cause mortality associated with short-term exposure to PM2.5, PM2.5-10, and PM10 in Italy, despite a decline in air pollution level.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Type of study:
Randomized controlled trials
Language:
English
Year:
2021
Document Type:
Article
Affiliation country:
Toxics9030056
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