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Increased antimicrobial resistance during the COVID-19 pandemic.
Lai, Chih-Cheng; Chen, Shey-Ying; Ko, Wen-Chien; Hsueh, Po-Ren.
  • Lai CC; Department of Internal Medicine, Kaohsiung Veterans General Hospital, Tainan Branch, Tainan, Taiwan.
  • Chen SY; Department of Emergency Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan; Center for Quality Management, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.
  • Ko WC; Department of Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
  • Hsueh PR; Department of Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan; Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address: hsporen@nt
Int J Antimicrob Agents ; 57(4): 106324, 2021 Apr.
Article in English | MEDLINE | ID: covidwho-1141886
ABSTRACT
In addition to SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection itself, an increase in the incidence of antimicrobial resistance poses collateral damage to the current status of the COVID-19 (coronavirus disease 2019) pandemic. There has been a rapid increase in multidrug-resistant organisms (MDROs), including extended-spectrum ß-lactamase (ESBL)-producing Klebsiella pneumoniae, carbapenem-resistant New Delhi metallo-ß-lactamase (NDM)-producing Enterobacterales, Acinetobacter baumannii, methicillin-resistant Staphylococcus aureus (MRSA), pan-echinocandin-resistant Candida glabrata and multi-triazole-resistant Aspergillus fumigatus. The cause is multifactorial and is particularly related to high rates of antimicrobial agent utilisation in COVID-19 patients with a relatively low rate of co- or secondary infection. Appropriate prescription and optimised use of antimicrobials according to the principles of antimicrobial stewardship as well as quality diagnosis and aggressive infection control measures may help prevent the occurrence of MDROs during this pandemic.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Bacterial Infections / Drug Resistance, Microbial / Coinfection / COVID-19 / Anti-Bacterial Agents / Mycoses Type of study: Observational study Topics: Long Covid Limits: Humans Language: English Journal: Int J Antimicrob Agents Year: 2021 Document Type: Article Affiliation country: J.ijantimicag.2021.106324

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Bacterial Infections / Drug Resistance, Microbial / Coinfection / COVID-19 / Anti-Bacterial Agents / Mycoses Type of study: Observational study Topics: Long Covid Limits: Humans Language: English Journal: Int J Antimicrob Agents Year: 2021 Document Type: Article Affiliation country: J.ijantimicag.2021.106324