[RNA polymerase: The Achilles heel of SARS-CoV-2].

Corteggiani, Marie; Gombert, Lucas; Pellegri, Callypso; Aussel, Laurent

[RNA polymerase: The Achilles heel of SARS-CoV-2]. / L'ARN polymérase COVID-19 - Le talon d'Achille du SARS-CoV-2.

Corteggiani, Marie; Gombert, Lucas; Pellegri, Callypso; Aussel, Laurent.

Corteggiani M; Master 2 Microbiologie intégrative et fondamentale, Aix Marseille Université, Marseille, France.
Gombert L; Master 2 Microbiologie intégrative et fondamentale, Aix Marseille Université, Marseille, France.
Pellegri C; Master 2 Microbiologie intégrative et fondamentale, Aix Marseille Université, Marseille, France.
Aussel L; Master 2 Microbiologie intégrative et fondamentale, Aix Marseille Université, Marseille, France.

Med Sci (Paris) ; 37(3): 288-292, 2021 03.

Article in French | MEDLINE | ID: covidwho-1142475

Subject(s)

Antiviral Agents; Coronavirus RNA-Dependent RNA Polymerase; Drug Discovery; SARS-CoV-2/physiology; Virus Replication/drug effects; Antimetabolites/chemistry; Antimetabolites/therapeutic use; Antiviral Agents/chemical synthesis; Antiviral Agents/therapeutic use; COVID-19/pathology; COVID-19/virology; Coronavirus RNA-Dependent RNA Polymerase/antagonists & inhibitors; Coronavirus RNA-Dependent RNA Polymerase/physiology; Drug Discovery/methods; Drug Discovery/trends; Humans; Molecular Targeted Therapy/methods; Molecular Targeted Therapy/trends; RNA, Viral/drug effects; RNA, Viral/genetics; RNA, Viral/metabolism; RNA-Dependent RNA Polymerase/antagonists & inhibitors; RNA-Dependent RNA Polymerase/physiology; Ribavirin/chemistry; Ribavirin/therapeutic use; SARS-CoV-2/drug effects; SARS-CoV-2/genetics; Virus Replication/genetics; COVID-19 Drug Treatment

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Virus Replication / Drug Discovery / Coronavirus RNA-Dependent RNA Polymerase / SARS-CoV-2 Limits: Humans Language: French Journal: Med Sci (Paris) Journal subject: Medicine Year: 2021 Document Type: Article Affiliation country: Medsci

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