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Increased blood angiotensin converting enzyme 2 activity in critically ill COVID-19 patients.
van Lier, Dirk; Kox, Matthijs; Santos, Karine; van der Hoeven, Hans; Pillay, Janesh; Pickkers, Peter.
  • van Lier D; Dept of Intensive Care Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands.
  • Kox M; Both authors contributed equally.
  • Santos K; Dept of Intensive Care Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands.
  • van der Hoeven H; Both authors contributed equally.
  • Pillay J; 4TEEN4 Pharmaceuticals GmbH, Hennigsdorf, Germany.
  • Pickkers P; Dept of Intensive Care Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands.
ERJ Open Res ; 7(1)2021 Jan.
Article in English | MEDLINE | ID: covidwho-1143170
ABSTRACT
Critically ill #COVID19 patients display markedly increased alternative angiotensin pathway activity compared to healthy controls, reflected by increased blood ACE2 levels as well as decreased angiotensin-II and enhanced angiotensin-1-7 formation https//bit.ly/2MU1z4z.

Full text: Available Collection: International databases Database: MEDLINE Language: English Year: 2021 Document Type: Article Affiliation country: 23120541.00848-2020

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Full text: Available Collection: International databases Database: MEDLINE Language: English Year: 2021 Document Type: Article Affiliation country: 23120541.00848-2020