A vicious circle between oxidative stress and cytokine storm in acute respiratory distress syndrome pathogenesis at covid-19 infection
Ukrainian Biochemical Journal
; 93(1):18-29, 2021.
Article
in English
| Scopus | ID: covidwho-1143877
ABSTRACT
In early December 2019, the pandemic of coronavirus disease 2019 (COVID-19) began in Wuhan City, Hubei Province, China. Since then, it has propagated rapidly and turned into a major global crisis due to the high virus spreading. Acute respiratory distress syndrome (ARDS) is considered as a defining cause of the death cases. Cytokine storm and oxidative stress are the main players of ARDS development during respiratory virus infections. In this review, we discussed molecular mechanisms of a fatal vicious circle between oxidative stress and cytokine storm during COVID-19 infection. We also described how aging can inflame the vicious circle. © 2021 Meftahi G. H. et al.
Full text:
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Collection:
Databases of international organizations
Database:
Scopus
Language:
English
Journal:
Ukrainian Biochemical Journal
Year:
2021
Document Type:
Article
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