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COVID-19-Related Neuropsychiatric Symptoms in Patients With Alcohol Abuse Conditions During the SARS-CoV-2 Pandemic: A Retrospective Cohort Study Using Real World Data From Electronic Health Records of a Tertiary Hospital.
Varela Rodríguez, Carolina; Arias Horcajadas, Francisco; Martín-Arriscado Arroba, Cristina; Combarro Ripoll, Carolina; Juanes Gonzalez, Alba; Esperesate Pajares, Marina; Rodrigo Holgado, Irene; Cadenas Manceñido, Álvaro; Sánchez Rodríguez, Laura; Baselga Penalva, Blanca; Marín, Marta; Rubio, Gabriel.
  • Varela Rodríguez C; Quality of Care Unit, Hospital Universitario 12 de Octubre, Madrid, Spain.
  • Arias Horcajadas F; Psychiatric Department, Hospital Universitario 12 de Octubre, Madrid, Spain.
  • Martín-Arriscado Arroba C; RETIC (Network of Addictive Conditions), Institute of Health Carlos III, Madrid, Spain.
  • Combarro Ripoll C; Research and Science Support Unit, Instituto de investigación Biomédica del Hospital Universitario 12 de Octubre I+12, Madrid, Spain.
  • Juanes Gonzalez A; Psychiatric Department, Hospital Universitario 12 de Octubre, Madrid, Spain.
  • Esperesate Pajares M; RETIC (Network of Addictive Conditions), Institute of Health Carlos III, Madrid, Spain.
  • Rodrigo Holgado I; Psychiatric Department, Hospital Universitario 12 de Octubre, Madrid, Spain.
  • Cadenas Manceñido Á; RETIC (Network of Addictive Conditions), Institute of Health Carlos III, Madrid, Spain.
  • Sánchez Rodríguez L; Psychiatric Department, Hospital Universitario 12 de Octubre, Madrid, Spain.
  • Baselga Penalva B; RETIC (Network of Addictive Conditions), Institute of Health Carlos III, Madrid, Spain.
  • Marín M; Psychiatric Department, Hospital Universitario 12 de Octubre, Madrid, Spain.
  • Rubio G; RETIC (Network of Addictive Conditions), Institute of Health Carlos III, Madrid, Spain.
Front Neurol ; 12: 630566, 2021.
Article in English | MEDLINE | ID: covidwho-1145569
ABSTRACT
Patients with an alcohol abuse disorder exhibit several medical characteristics and social determinants, which suggest a greater vulnerability to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and a worse course of the coronavirus disease 2019 (COVID-19) once infected. During the first wave of the COVID-19, most of the countries have register an increase in alcohol consumption. However, studies on the impact of alcohol addiction on the risk of COVID-19 infection are very scarce and inconclusive. This research offers a descriptive observational retrospective cohort study using real world data obtained from the Electronic Health Records. We found that patients with a personal history of alcohol abuse were 8% more likely to extend their hospitalization length of stay for 1 day (95% CI = 1.04-1.12) and 15% more likely to extend their Intensive Care Unit (ICU) length of stay (95% CI = 1.01-1.30). They were also 5.47 times more at risk of needing an ICU admission (95% CI = 1.61-18.57) and 3.54 times (95% CI = 1.51-8.30) more at risk of needing a respirator. Regarding COVID-19 symptoms, patients with a personal history of alcohol abuse were 91% more likely of exhibiting dyspnea (95% CI = 1.03-3.55) and 3.15 times more at risk of showing at least one neuropsychiatric symptom (95% CI = 1.61-6.17). In addition, they showed statistically significant differences in the number of neuropsychiatric symptoms developed during the COVID-19 infection. Therefore, we strongly recommend to warn of the negative consequences of alcohol abuse over COVID-19 complications. For this purpose. Clinicians should systematically assess history of alcohol issues and drinking habits in all patients, especially for those who seek medical advice regarding COVID-19 infection, in order to predict its severity of symptoms and potential complications. Moreover, this information should be included, in a structured field, into the Electronic Health Record to facilitate the automatic extraction of data, in real time, useful to evaluate the decision-making process in a dynamic context.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study Language: English Journal: Front Neurol Year: 2021 Document Type: Article Affiliation country: Fneur.2021.630566

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study Language: English Journal: Front Neurol Year: 2021 Document Type: Article Affiliation country: Fneur.2021.630566