Experimental SARS-CoV-2 Infection of Bank Voles.

Ulrich, Lorenz; Michelitsch, Anna; Halwe, Nico; Wernike, Kerstin; Hoffmann, Donata; Beer, Martin

Ulrich, Lorenz; Michelitsch, Anna; Halwe, Nico; Wernike, Kerstin; Hoffmann, Donata; Beer, Martin.

Emerg Infect Dis ; 27(4): 1193-1195, 2021 04.

Article in English | MEDLINE | ID: covidwho-1146550

ABSTRACT

ABSTRACT

After experimental inoculation, severe acute respiratory syndrome coronavirus 2 infection was confirmed in bank voles by seroconversion within 8 days and detection of viral RNA in nasal tissue for up to 21 days. However, transmission to contact animals was not detected. Thus, bank voles are unlikely to establish effective transmission cycles in nature.

Subject(s)

Arvicolinae; COVID-19; Disease Transmission, Infectious; Rodent Diseases; Seroconversion; Virus Shedding; Animals; Antibodies, Viral; COVID-19/immunology; COVID-19/transmission; COVID-19/virology; COVID-19 Serological Testing; Disease Models, Animal; Disease Susceptibility; Nasal Mucosa/virology; Rodent Diseases/immunology; Rodent Diseases/transmission; Rodent Diseases/virology

Keywords

2019 novel coronavirus disease; COVID-19; Germany; SARS-CoV-2; bank vole; coronavirus; coronavirus disease; respiratory infections; rodent; serology; severe acute respiratory syndrome coronavirus 2; susceptibility; sylvatic cycle; viruses; wildlife cycle; zoonoses

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Rodent Diseases / Arvicolinae / Virus Shedding / Disease Transmission, Infectious / Seroconversion / COVID-19 Limits: Animals Language: English Journal: Emerg Infect Dis Journal subject: Communicable Diseases Year: 2021 Document Type: Article

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