Immune reconstitution and severity of COVID-19 among hematopoietic cell transplant recipients.
Transpl Infect Dis
; 23(4): e13606, 2021 Aug.
Article
in English
| MEDLINE | ID: covidwho-1146666
ABSTRACT
Severe acute respiratory syndrome coronavirus 2 can lead to life-threatening coronavirus disease 2019 (COVID-19) infections in patients with hematologic malignancies, particularly among hematopoietic cell transplant (HCT) recipients. We describe two patients with COVID-19 during the pre-engraftment period after HCT and review previous reports of COVID-19 in HCT recipients. Because of significant mortality from COVID-19, primarily after allogeneic HCT, early, preemptive, and optimal directed therapy may improve outcomes and reduce the mortality rate but still needs to be established in clinical trials.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Hematopoietic Stem Cell Transplantation
/
Immune Reconstitution
/
COVID-19
Type of study:
Case report
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
Transpl Infect Dis
Journal subject:
Transplantation
Year:
2021
Document Type:
Article
Affiliation country:
Tid.13606
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