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Multiwave pandemic dynamics explained: how to tame the next wave of infectious diseases.
Cacciapaglia, Giacomo; Cot, Corentin; Sannino, Francesco.
  • Cacciapaglia G; Institut de Physique des 2 Infinis (IP2I), CNRS/IN2P3, UMR5822, 69622, Villeurbanne, France. g.cacciapaglia@ipnl.in2p3.fr.
  • Cot C; Université de Lyon, Université Claude Bernard Lyon 1, 69001, Lyon, France. g.cacciapaglia@ipnl.in2p3.fr.
  • Sannino F; Institut de Physique des 2 Infinis (IP2I), CNRS/IN2P3, UMR5822, 69622, Villeurbanne, France.
Sci Rep ; 11(1): 6638, 2021 03 23.
Article in English | MEDLINE | ID: covidwho-1147847
ABSTRACT
Pandemics, like the 1918 Spanish Influenza and COVID-19, spread through regions of the World in subsequent waves. Here we propose a consistent picture of the wave pattern based on the epidemic Renormalisation Group (eRG) framework, which is guided by the global symmetries of the system under time rescaling. We show that the rate of spreading of the disease can be interpreted as a time-dilation symmetry, while the final stage of an epidemic episode corresponds to reaching a time scale-invariant state. We find that the endemic period between two waves is a sign of instability in the system, associated to near-breaking of the time scale-invariance. This phenomenon can be described in terms of an eRG model featuring complex fixed points. Our results demonstrate that the key to control the arrival of the next wave of a pandemic is in the strolling period in between waves, i.e. when the number of infections grows linearly. Thus, limiting the virus diffusion in this period is the most effective way to prevent or delay the arrival of the next wave. In this work we establish a new guiding principle for the formulation of mid-term governmental strategies to curb pandemics and avoid recurrent waves of infections, deleterious in terms of human life loss and economic damage.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Influenza, Human / COVID-19 / Models, Theoretical Type of study: Observational study Limits: Humans Language: English Journal: Sci Rep Year: 2021 Document Type: Article Affiliation country: S41598-021-85875-2

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Influenza, Human / COVID-19 / Models, Theoretical Type of study: Observational study Limits: Humans Language: English Journal: Sci Rep Year: 2021 Document Type: Article Affiliation country: S41598-021-85875-2