Geographic Differences in Lung Transplant Volume and Donor Availability During the COVID-19 Pandemic.
Transplantation
; 105(4): 861-866, 2021 04 01.
Article
in English
| MEDLINE | ID: covidwho-1148015
ABSTRACT
BACKGROUND:
Regional variation in lung transplantation practices due to local coronavirus disease 2019 (COVID-19) prevalence may cause geographic disparities in access to lung transplantation.METHODS:
Using the United Network for Organ Sharing registry, we conducted a descriptive analysis of lung transplant volume, donor lung volume, new waitlist activations, and waiting list deaths at high-volume lung transplant centers during the first 3 months of the pandemic (March 1. 2020, to May 30, 2020) and we compared it to the same period in the preceding 5 years.RESULTS:
Lung transplant volume decreased by 10% nationally and by a median of 50% in high COVID-19 prevalence centers (range -87% to 80%) compared with a median increase of 10% (range -87% to 80%) in low prevalence centers (P-for-trend 0.006). Donation services areas with high COVID-19 prevalence experienced a greater decrease in organ availability (-28% range, -72% to -11%) compared with low prevalence areas (+7%, range -20% to + 55%, P-for-trend 0.001). Waiting list activations decreased at 18 of 22 centers. Waiting list deaths were similar to the preceding 5 years and independent of local COVID-19 prevalence (P-for-trend 0.36).CONCLUSIONS:
Regional variation in transplantation and donor availability in the early months of the pandemic varied by local COVID-19 activity.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Tissue and Organ Procurement
/
Lung Transplantation
/
Pandemics
/
SARS-CoV-2
/
COVID-19
Type of study:
Cohort study
/
Observational study
/
Prognostic study
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
/
Young adult
Country/Region as subject:
North America
Language:
English
Journal:
Transplantation
Year:
2021
Document Type:
Article
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