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Eleven faces of coronavirus disease 2019.
Dong, Xiang; Cao, Yi-Yuan; Lu, Xiao-Xia; Zhang, Jin-Jin; Du, Hui; Yan, You-Qin; Akdis, Cezmi A; Gao, Ya-Dong.
  • Dong X; Department of Allergology, Zhongnan Hospital of Wuhan University, Wuhan, China.
  • Cao YY; Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China.
  • Lu XX; Department of Respiratory Medicine, Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Zhang JJ; Department of Allergology, Zhongnan Hospital of Wuhan University, Wuhan, China.
  • Du H; Department of Respiratory Medicine, Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Yan YQ; Department of Infectious Disease, No. 7 Hospital of Wuhan, Wuhan, China.
  • Akdis CA; Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland.
  • Gao YD; Department of Allergology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Allergy ; 75(7): 1699-1709, 2020 07.
Article in English | MEDLINE | ID: covidwho-11481
ABSTRACT
BACKGROUND AND

AIMS:

The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has recently spread worldwide and been declared a pandemic. We aim to describe here the various clinical presentations of this disease by examining eleven cases.

METHODS:

Electronic medical records of 11 patients with COVID-19 were collected, and demographics, clinical manifestations, outcomes, key laboratory results, and radiological images are discussed.

RESULTS:

The clinical course of the eleven cases demonstrated the complexity of the COVID-19 profile with different clinical presentations. Clinical manifestations range from asymptomatic cases to patients with mild and severe symptoms, with or without pneumonia. Laboratory detection of the viral nucleic acid can yield false-negative results, and serological testing of virus-specific IgG and IgM antibodies should be used as an alternative for diagnosis. Patients with common allergic diseases did not develop distinct symptoms and severe courses. Cases with a pre-existing condition of chronic obstructive pulmonary disease or complicated with a secondary bacterial pneumonia were more severe.

CONCLUSION:

All different clinical characteristics of COVID-19 should be taken into consideration to identify patients that need to be in strict quarantine for the efficient containment of the pandemic.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Betacoronavirus Type of study: Case report / Diagnostic study / Prognostic study Limits: Adult / Aged / Child, preschool / Female / Humans / Male / Middle aged / Young adult Language: English Journal: Allergy Year: 2020 Document Type: Article Affiliation country: All.14289

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections / Betacoronavirus Type of study: Case report / Diagnostic study / Prognostic study Limits: Adult / Aged / Child, preschool / Female / Humans / Male / Middle aged / Young adult Language: English Journal: Allergy Year: 2020 Document Type: Article Affiliation country: All.14289