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Unusual aetiology of respiratory compromise in a patient with AIDS.
Maaliki, Naji; Ali, Aleem Azal; Isache, Carmen Liliana; Aung, Win.
  • Maaliki N; Internal Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida, USA naji.maaliki@jax.ufl.edu.
  • Ali AA; Internal Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida, USA.
  • Isache CL; Infectious Diseases, University of Florida Health at Jacksonville, Jacksonville, Florida, USA.
  • Aung W; Internal Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, Florida, USA.
BMJ Case Rep ; 14(3)2021 Mar 23.
Article in English | MEDLINE | ID: covidwho-1148109
ABSTRACT
A 36-year-old African American man with no medical history presented with a recent history of cough and dyspnoea. Initial chest imaging revealed diffuse bilateral lung infiltrates. A subsequent HIV test resulted positive, and he was presumptively diagnosed with AIDS, later confirmed by a CD4 of 88 cells/mm3 Empiric therapy with trimethoprim-sulfamethoxazole was initiated for presumed Pneumocystis jirovecii pneumonia. The patient's clinical status deteriorated despite treatment. Further workup with chest CT, bronchoscopy and skin biopsy led to a diagnosis of Kaposi sarcoma with pulmonary involvement. Highly active antiretroviral therapy therapy was initiated, along with plans to start chemotherapy. However, the patient's clinical status rapidly declined, leading to respiratory failure and eventual death. This case underlines the importance of maintaining a broad differential in immunocompromised patients presenting with respiratory symptoms.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Pneumocystis / Sarcoma, Kaposi / Acquired Immunodeficiency Syndrome / Pneumocystis carinii Type of study: Diagnostic study / Etiology study / Prognostic study Topics: Long Covid Limits: Adult / Humans / Male Language: English Year: 2021 Document Type: Article Affiliation country: Bcr-2020-240849

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Pneumocystis / Sarcoma, Kaposi / Acquired Immunodeficiency Syndrome / Pneumocystis carinii Type of study: Diagnostic study / Etiology study / Prognostic study Topics: Long Covid Limits: Adult / Humans / Male Language: English Year: 2021 Document Type: Article Affiliation country: Bcr-2020-240849