Enrichment of CCR6+ CD8+ T cells and CCL20 in the lungs of mechanically ventilated patients with COVID-19.
Eur J Immunol
; 51(6): 1535-1538, 2021 06.
Article
in English
| MEDLINE | ID: covidwho-1151896
ABSTRACT
Despite high levels of CXCR3 ligands in mechanically ventilated COVID-19 patients, BALF CD8 T cells were not enriched in CXCR3+ cells but rather CCR6+ , likely due to high CCL20 levels in BALF, and had very high PD-1 expression. In mechanically ventilated, but not ward, patients Th-1 immunity is impaired. â.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Respiration, Artificial
/
CD8-Positive T-Lymphocytes
/
Chemokine CCL20
/
Receptors, CCR6
/
SARS-CoV-2
/
COVID-19
/
Lung
Limits:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
English
Journal:
Eur J Immunol
Year:
2021
Document Type:
Article
Affiliation country:
Eji.202049046
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