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Early Virus Clearance and Delayed Antibody Response in a Case of Coronavirus Disease 2019 (COVID-19) With a History of Coinfection With Human Immunodeficiency Virus Type 1 and Hepatitis C Virus.
Zhao, Juanjuan; Liao, Xuejiao; Wang, Haiyan; Wei, Lanlan; Xing, Mingzhao; Liu, Lei; Zhang, Zheng.
  • Zhao J; Institute of Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital, Shenzhen, Guangdong, China.
  • Liao X; Institute of Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital, Shenzhen, Guangdong, China.
  • Wang H; Institute of Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital, Shenzhen, Guangdong, China.
  • Wei L; Institute of Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital, Shenzhen, Guangdong, China.
  • Xing M; School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, China.
  • Liu L; Institute of Hepatology, National Clinical Research Center for Infectious Disease, Shenzhen Third People's Hospital, Shenzhen, Guangdong, China.
  • Zhang Z; School of Medicine, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Clin Infect Dis ; 71(16): 2233-2235, 2020 11 19.
Article in English | MEDLINE | ID: covidwho-1153143
ABSTRACT
The effect of host immune status on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection remains unknown. Here, we report the first case of coronavirus disease 2019 (COVID-19) with human immunodeficiency virus type 1 (HIV-1)/hepatitis C virus coinfection, who showed a persistently negative SARS-CoV-2 RNA test but delayed antibody response in the plasma. This case highlights the influence of HIV-1-induced immune dysfunction on early SARS-CoV-2 clearance.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: HIV Infections / Hepatitis C / Coinfection / COVID-19 / Antibodies, Viral Type of study: Case report / Diagnostic study / Observational study / Prognostic study Topics: Long Covid Limits: Adult / Humans / Male Language: English Journal: Clin Infect Dis Journal subject: Communicable Diseases Year: 2020 Document Type: Article Affiliation country: Cid

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Full text: Available Collection: International databases Database: MEDLINE Main subject: HIV Infections / Hepatitis C / Coinfection / COVID-19 / Antibodies, Viral Type of study: Case report / Diagnostic study / Observational study / Prognostic study Topics: Long Covid Limits: Adult / Humans / Male Language: English Journal: Clin Infect Dis Journal subject: Communicable Diseases Year: 2020 Document Type: Article Affiliation country: Cid