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Tuberculosis and COVID-19 Co-infection: An Updated Review.
Mishra, Ajay; George, Anu Anna; Sahu, Kamal Kant; Lal, Amos; Abraham, George.
  • Mishra A; . ajay.mishra@stvincenthospital.com.
  • George AA; Resident in Internal Medicine. anugeorg@gmail.com.
  • Sahu KK; Resident in Internal Medicine. Kamalkant.Sahu@stvincenthospital.com.
  • Lal A; Fellow, Department of Critical Care and Pulmonary Medicine, Mayo Clinic, Rochester, MN . Lal.Amos@mayo.edu.
  • Abraham G; Chief of Medicine, Saint Vincent Hospital Professor of Medicine, University of Massachusetts Medical School President-Elect and Regent, American College of Physicians (ACP) Chair, Infectious Disease Board, American Board of Internal Medicine (ABIM) Chair, Board of Registration in Medicine (BORIM), C
Acta Biomed ; 92(1): e2021025, 2020 11 10.
Article in English | MEDLINE | ID: covidwho-1155016
ABSTRACT
Coronavirus disease (COVID 19) has involved millions of people all over the world. Tuberculosis (TB) continues to affect millions of people every year with high mortality. There is limited literature on the occurrence of COVID 19 in patients with TB. We reviewed the available data on various clinical details, management, and outcome among patients with COVID-19 and TB. 8 studies reported a total of 80 patients with this coinfection. These patients were reported from ten different countries, with Italy reporting the largest number of cases. Migrant, males constituted a major proportion of cases. Most reported patients were symptomatic. Fever, dry cough, and dyspnea were the most commonly reported symptoms. Bilateral ground glass opacities were more common in COVID 19 infection and cavitary lesions were more common in patients with TB. Most reported TB patients had been found to have mycobacterium tuberculosis from sputum culture in the background of pulmonary TB. Most patients of TB were treated with multidrug regimen antitubercular therapy. In all 8 studies, COVID 19 was treated as per the local protocol. Mortality was reported in more than 10% of patients. Mortality was higher in elderly patients (> 70 years) and amongst patient with multiple medical comorbidities.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Tuberculosis / Coinfection / SARS-CoV-2 / COVID-19 Drug Treatment Type of study: Observational study / Prognostic study Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: English Journal: Acta Biomed Journal subject: Medicine Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Tuberculosis / Coinfection / SARS-CoV-2 / COVID-19 Drug Treatment Type of study: Observational study / Prognostic study Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: English Journal: Acta Biomed Journal subject: Medicine Year: 2020 Document Type: Article