Two Possible Mechanisms of Disease in COVID-19

ABSTRACT

At the population level, indiscriminate cessation of these drugs would lead to uncontrolled hypertension, heart failure, and other unintended consequences. [...]understanding whether these commonly used drugs truly contribute to mortality in COVID-19 demanded investigation. In their statistical models, older age and heart disease were independently associated with in-hospital mortality, but use of ACE inhibitors and ARBs was not. [...]ACE inhibitors may have been protective.