Contact Isolation Is Not Better than Standard Precautions for Decreasing Acquisition of ESBL-Producing Enterobacterales

ABSTRACT

Antibiotic consumption at the ward level did not differ between intervention protocols. [...]there was no difference in acquisition of ESBL-producing E. coli (which made up 73% of cases) and K. pneumonia between contact isolation and standard precautions. [...]the delay in laboratory turnaround time in reporting ESBL-E positive samples (median four days, range three to five days) led to delays in implementing contact isolation. [...]evidence suggests that patient-to-patient transmission is not the main pathway for the spread of ESBL-E.