Management considerations for stroke-like episodes in MELAS with concurrent COVID-19 infection.
J Neurol
; 268(11): 3988-3991, 2021 Nov.
Article
in English
| MEDLINE | ID: covidwho-1163035
ABSTRACT
There have been considerations since the beginning of the Coronavirus pandemic that COVID-19 infection, like any other viral illness, can trigger neurological and metabolic decompensation in patients with mitochondrial diseases. At the time of writing, there were no published reports reviewing experiences and guidelines about management of COVID-19 infection in this patient population. We present a challenging case of an adult patient with a known diagnosis of Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS) complicated by COVID-19 infection. She initially presented with altered mental status and vomiting and went on to develop a stroke-like episode, pancreatitis, and pneumatosis intestinalis. We review salient features of her hospitalization, including initiation of thromboprophylaxis in relation to intravenous arginine therapy, caution regarding medications such as remdesivir, and the incidence of gastrointestinal complications.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Acidosis, Lactic
/
MELAS Syndrome
/
Stroke
/
Venous Thromboembolism
/
COVID-19
Type of study:
Case report
/
Observational study
/
Qualitative research
Topics:
Long Covid
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
J Neurol
Year:
2021
Document Type:
Article
Affiliation country:
S00415-021-10538-1
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