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The novel Mechanical Ventilator Milano for the COVID-19 pandemic.
Abba, A; Accorsi, C; Agnes, P; Alessi, E; Amaudruz, P; Annovi, A; Desages, F Ardellier; Back, S; Badia, C; Bagger, J; Basile, V; Batignani, G; Bayo, A; Bell, B; Beschi, M; Biagini, D; Bianchi, G; Bicelli, S; Bishop, D; Boccali, T; Bombarda, A; Bonfanti, S; Bonivento, W M; Bouchard, M; Breviario, M; Brice, S; Brown, R; Calvo-Mozota, J M; Camozzi, L; Camozzi, M; Capra, A; Caravati, M; Carlini, M; Ceccanti, A; Celano, B; Cela Ruiz, J M; Charette, C; Cogliati, G; Constable, M; Crippa, C; Croci, G; Cudmore, S; Dahl, C E; Dal Molin, A; Daley, M; Di Guardo, C; D'Avenio, G; Davignon, O; Del Tutto, M; De Ruiter, J.
  • Abba A; Nuclear Instruments S.R.L., Como 22045, Italy.
  • Accorsi C; Elemaster Group S.p.A., Lomagna (LC) 23871, Italy.
  • Agnes P; Department of Physics, University of Houston, Houston, Texas 77204, USA.
  • Alessi E; Istituto per la Scienza e Tecnologia dei Plasmi, ISTP-CNR, Milano 20125, Italy.
  • Amaudruz P; TRIUMF, Vancouver, British Columbia V6T 2A3, Canada.
  • Annovi A; INFN Sezione di Pisa, Pisa 56127, Italy.
  • Desages FA; APC, Université de Paris, CNRS, Astroparticule et Cosmologie, F-75013 Paris, France.
  • Back S; SNOLAB, Lively, Ontario P3Y 1N2, Canada.
  • Badia C; Gran Sasso Science Institute, L'Aquila 67100, Italy.
  • Bagger J; TRIUMF, Vancouver, British Columbia V6T 2A3, Canada.
  • Basile V; Istituto di Sistemi e Tecnologie Industriali Intelligenti per il Manifatturiero Avanzato, CNR STIIMA, Milano 20133, Italy.
  • Bayo A; LSC, Laboratorio Subterráneo de Canfranc, Canfranc-Estación 22880, Spain.
  • Bell B; JMP Solutions, London, Ontario N6N 1E2, Canada.
  • Biagini D; Dipartimento di Chimica e Chimica Industriale, Università di Pisa, Pisa 56124, Italy.
  • Bianchi G; Istituto di Sistemi e Tecnologie Industriali Intelligenti per il Manifatturiero Avanzato, CNR STIIMA, Milano 20133, Italy.
  • Bicelli S; Camozzi Group S.p.A., Brescia BS 25126, Italy.
  • Bishop D; TRIUMF, Vancouver, British Columbia V6T 2A3, Canada.
  • Boccali T; INFN Sezione di Pisa, Pisa 56127, Italy.
  • Bombarda A; Dipartimento di Ingegneria Gestionale, dell'Informazione e della Produzione, Università di Bergamo, Bergamo, 24129, Italy.
  • Bonfanti S; Dipartimento di Ingegneria Gestionale, dell'Informazione e della Produzione, Università di Bergamo, Bergamo, 24129, Italy.
  • Bonivento WM; INFN Sezione di Cagliari, Cagliari 09042, Italy.
  • Bouchard M; Canadian Nuclear Laboratories, Chalk River K0J 1J0, Canada.
  • Breviario M; Elemaster Group S.p.A., Lomagna (LC) 23871, Italy.
  • Brice S; Fermi National Accelerator Laboratory, Batavia, Illinois 60510, USA.
  • Brown R; Canadian Nuclear Laboratories, Chalk River K0J 1J0, Canada.
  • Calvo-Mozota JM; LSC, Laboratorio Subterráneo de Canfranc, Canfranc-Estación 22880, Spain.
  • Camozzi L; Camozzi Group S.p.A., Brescia BS 25126, Italy.
  • Camozzi M; Camozzi Group S.p.A., Brescia BS 25126, Italy.
  • Capra A; TRIUMF, Vancouver, British Columbia V6T 2A3, Canada.
  • Caravati M; INFN Sezione di Cagliari, Cagliari 09042, Italy.
  • Carlini M; Gran Sasso Science Institute, L'Aquila 67100, Italy.
  • Ceccanti A; INFN-CNAF, Bologna 40127, Italy.
  • Celano B; INFN Sezione di Napoli, Napoli 80126, Italy.
  • Cela Ruiz JM; CIEMAT, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas, Madrid 28040, Spain.
  • Charette C; Canadian Nuclear Laboratories, Chalk River K0J 1J0, Canada.
  • Cogliati G; Elemaster Group S.p.A., Lomagna (LC) 23871, Italy.
  • Constable M; TRIUMF, Vancouver, British Columbia V6T 2A3, Canada.
  • Crippa C; Elemaster Group S.p.A., Lomagna (LC) 23871, Italy.
  • Croci G; Dipartimento di Fisica, Università di Milano-Bicocca, Milano 20126, Italy.
  • Cudmore S; Canadian Nuclear Laboratories, Chalk River K0J 1J0, Canada.
  • Dal Molin A; Dipartimento di Fisica, Università di Milano-Bicocca, Milano 20126, Italy.
  • Daley M; Canadian Nuclear Laboratories, Chalk River K0J 1J0, Canada.
  • Di Guardo C; Dipartimento di Scienze Economiche ed Aziendali, Università degli Studi di Cagliari, Cagliari 09042, Italy.
  • D'Avenio G; National Center for Innovative Technologies in Public Health, ISS (Italy National Institute of Health), Roma 00161, Italy.
  • Davignon O; Laboratoire Leprince Ringuet, École Polytechnique, Palaiseau, Cedex 91128, France.
  • Del Tutto M; Fermi National Accelerator Laboratory, Batavia, Illinois 60510, USA.
  • De Ruiter J; Canadian Nuclear Laboratories, Chalk River K0J 1J0, Canada.
Phys Fluids (1994) ; 33(3): 037122, 2021 Mar.
Article in English | MEDLINE | ID: covidwho-1165006
ABSTRACT
This paper presents the Mechanical Ventilator Milano (MVM), a novel intensive therapy mechanical ventilator designed for rapid, large-scale, low-cost production for the COVID-19 pandemic. Free of moving mechanical parts and requiring only a source of compressed oxygen and medical air to operate, the MVM is designed to support the long-term invasive ventilation often required for COVID-19 patients and operates in pressure-regulated ventilation modes, which minimize the risk of furthering lung trauma. The MVM was extensively tested against ISO standards in the laboratory using a breathing simulator, with good agreement between input and measured breathing parameters and performing correctly in response to fault conditions and stability tests. The MVM has obtained Emergency Use Authorization by U.S. Food and Drug Administration (FDA) for use in healthcare settings during the COVID-19 pandemic and Health Canada Medical Device Authorization for Importation or Sale, under Interim Order for Use in Relation to COVID-19. Following these certifications, mass production is ongoing and distribution is under way in several countries. The MVM was designed, tested, prepared for certification, and mass produced in the space of a few months by a unique collaboration of respiratory healthcare professionals and experimental physicists, working with industrial partners, and is an excellent ventilator candidate for this pandemic anywhere in the world.

Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Language: English Journal: Phys Fluids (1994) Year: 2021 Document Type: Article Affiliation country: 5.0044445

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Language: English Journal: Phys Fluids (1994) Year: 2021 Document Type: Article Affiliation country: 5.0044445