An inflammatory profile correlates with decreased frequency of cytotoxic cells in coronavirus disease 2019. (COVID special issue #2.)
Clinical Infectious Diseases
; 71(16):2272-2275, 2020.
Article
in English
| CAB Abstracts | ID: covidwho-1165366
ABSTRACT
Increased production of inflammatory cytokines and myeloid-derived suppressor cells occurs in patients with coronavirus disease 2019. These inversely correlated with perforin-expressing natural killer (NK) and CD3<sup>+</sup> T cells. We observed a lower number of perforin-expressing NK cells in intensive care unit (ICU) patients compared with non-ICU patients, suggesting an impairment of the immune cytotoxic arm as a pathogenic mechanism.
Full text:
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Collection:
Databases of international organizations
Database:
CAB Abstracts
Language:
English
Journal:
Clinical Infectious Diseases
Year:
2020
Document Type:
Article
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