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Management of anaphylaxis due to COVID-19 vaccines in the elderly.
Bousquet, Jean; Agache, Ioana; Blain, Hubert; Jutel, Marek; Ventura, Maria Teresa; Worm, Margitta; Del Giacco, Stefano; Benetos, Athanasios; Bilo, Beatrice Maria; Czarlewski, Wienczyslawa; Abdul Latiff, Amir Hamzah; Al-Ahmad, Mona; Angier, Elizabeth; Annesi-Maesano, Isabella; Atanaskovic-Markovic, Marina; Bachert, Claus; Barbaud, Annick; Bedbrook, Anna; Bennoor, Kazi S; Berghea, Elena Camelia; Bindslev-Jensen, Carsten; Bonini, Sergio; Bosnic-Anticevich, Sinthia; Brockow, Knut; Brussino, Luisa; Camargos, Paulo; Canonica, G Walter; Cardona, Victoria; Carreiro-Martins, Pedro; Carriazo, Ana; Casale, Thomas; Caubet, Jean-Christoph; Cecchi, Lorenzo; Cherubini, Antonio; Christoff, George; Chu, Derek K; Cruz, Alvaro A; Dokic, Dejan; El-Gamal, Yehia; Ebisawa, Motohiro; Eberlein, Bernadette; Farrell, John; Fernandez-Rivas, Montserrat; Fokkens, Wytske J; Fonseca, Joao A; Gao, Yadong; Gavazzi, Gaëtan; Gawlik, Radoslaw; Gelincik, Asli; Gemicioglu, Bilun.
  • Bousquet J; Department of Dermatology and Allergy, Comprehensive Allergy Center, Charité Universitätsmedizin Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.
  • Agache I; University Hospital Montpellier, France.
  • Blain H; MACVIA-France, Montpellier, France.
  • Jutel M; Faculty of Medicine, Transylvania University, Brasov, Romania.
  • Ventura MT; Department of Geriatrics, Montpellier University Hospital, Montpellier, France.
  • Worm M; Department of Clinical Immunology, Wroclaw Medical University, Wroclaw, Poland.
  • Del Giacco S; ALL-MED Medical Research Institute, Wroclaw, Poland.
  • Benetos A; University of Bari Medical School, Unit of Geriatric Immunoallergology, Bari, Italy.
  • Bilo BM; Department of Dermatology and Allergy, Comprehensive Allergy Center, Charité Universitätsmedizin Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.
  • Czarlewski W; Department of Medical Sciences and Public Health, Unit of Allergy and Clinical Immunology, University Hospital "Duilio Casula", University of Cagliari, Cagliari, Italy.
  • Abdul Latiff AH; Department of Geriatrics, CHRU de Nancy and Inserm DCAC, Université de Lorraine, Nancy, France.
  • Al-Ahmad M; Allergy Unit, Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, Italy.
  • Angier E; Department of Internal Medicine, University Hospital, Ospedali Riuniti di Ancona, Ancona, Italy.
  • Annesi-Maesano I; Medical Consulting Czarlewski, Levallois, France.
  • Atanaskovic-Markovic M; Department of Pediatrics, Allergy & Immunology Centre, Pantai Hospital, Universiti Putra Malaysia Teaching Hospital, Kuala Lumpur, Malaysia.
  • Bachert C; Microbiology Department, Faculty of Medicine, Kuwait University, Kuwait City, Kuwait.
  • Barbaud A; Department of Allergy, Al-Rashed Allergy Center, Kuwait City, Kuwait.
  • Bedbrook A; Primary Care and Population Sciences, University of Southampton, Southampton, UK.
  • Bennoor KS; Institut Desbrest d'Epidémiologie et Santé Publique (IDESP), INSERM et Université de Montpellier, Montpellier, France.
  • Berghea EC; Faculty of Medicine, University Children's Hospital, University of Belgrade, Belgrade, Serbia.
  • Bindslev-Jensen C; Upper Airways Research Laboratory, ENT Department, Ghent University Hospital, Ghent, Belgium.
  • Bonini S; International Airway Research Center, Sun Yat-sen University, First Affiliated Hospital Guangzou, China.
  • Bosnic-Anticevich S; Division of ENT Diseases, CLINTEC, Karolinska Institutet, Stockholm, Sweden.
  • Brockow K; Department of ENT Diseases, Karolinska University Hospital, Stockholm, Sweden.
  • Brussino L; Division of Service de Dermatologie et Allergologie, Hôpital Tenon, Paris, France.
  • Camargos P; Division of Equipe PEPITES, Sorbonne Université, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Paris, France.
  • Canonica GW; Department of Pediatrics, Allergy & Immunology Centre, Pantai Hospital, Universiti Putra Malaysia Teaching Hospital, Kuala Lumpur, Malaysia.
  • Cardona V; Department of Respiratory Medicine, National Institute of Diseases of the Chest and Hospital, Dhaka, Bangladesh.
  • Carreiro-Martins P; Allergology and Clinical Immunology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
  • Carriazo A; Clinical Emergency Hospital for Children MS Curie, Bucharest, Romania.
  • Casale T; Department of Dermatology and Allergy Centre, Odense University Hospital, Odense Research Center for Anaphylaxis (ORCA), Odense, Denmark.
  • Caubet JC; Institute of Translational Pharmacology, Italian National Research Council, Rome, Italy.
  • Cecchi L; Woolcock Institute of Medical Research, University of Sydney, Glebe, NSW, Australia.
  • Cherubini A; Woolcock Emphysema Centre, Sydney Local Health District, Glebe, NSW, Australia.
  • Christoff G; Department of Dermatology and Allergy Biederstein, School of Medicine, Technical University of Munich, Munich, Germany.
  • Chu DK; Department of Medical Sciences, Allergy and Clinical Immunology Unit, University of Torino & Mauriziano Hospital, Torino, Italy.
  • Cruz AA; Department of Pediatrics, Medical School, Federal University of Minas Gerais, Belo Horizonte, Brazil.
  • Dokic D; Department of Biomedical Sciences, Humanitas University, Milan, Italy.
  • El-Gamal Y; IRCCS Humanitas Research Hospital, Personalized Medicine, Asthma and Allergy, Milan, Italy.
  • Ebisawa M; Allergy Section, Department of Internal Medicine, Hospital Vall d'Hebron, Barcelona, Spain.
  • Eberlein B; ARADyAL Research Network, Barcelona, Spain.
  • Farrell J; Serviço de Imunoalergologia, Hospital de Dona Estefânia, Centro Hospitalar de Lisboa Central, Lisbon, Portugal.
  • Fernandez-Rivas M; Faculdade de Ciências Médicas (FCM), CEDOC, Universidade Nova de Lisboa, Lisbon, Portugal.
  • Fokkens WJ; Regional Ministry of Health of Andalusia, Seville, Spain.
  • Fonseca JA; Division of Allergy/Immunology, University of South Florida, Tampa, FL, USA.
  • Gao Y; Pediatric Allergy Unit, Department of Child and Adolescent, Geneva University Hospital, Geneva, Switzerland.
  • Gavazzi G; SOS Allergology and Clinical Immunology, USL Toscana Centro, Prato, Italy.
  • Gawlik R; Geriatria, Accettazione Geriatrica e Centro di Ricerca per l'invecchiamento, IRCCS INRCA, Ancona, Italy.
  • Gelincik A; Faculty of Public Health, Medical University, Sofia, Bulgaria.
  • Gemicioglu B; Department of Medicine and Health Research Methods, Evidence & Impact, McMaster University, Hamilton, ON, Canada.
Allergy ; 76(10): 2952-2964, 2021 10.
Article in English | MEDLINE | ID: covidwho-1165737
ABSTRACT
Older adults, especially men and/or those with diabetes, hypertension, and/or obesity, are prone to severe COVID-19. In some countries, older adults, particularly those residing in nursing homes, have been prioritized to receive COVID-19 vaccines due to high risk of death. In very rare instances, the COVID-19 vaccines can induce anaphylaxis, and the management of anaphylaxis in older people should be considered carefully. An ARIA-EAACI-EuGMS (Allergic Rhinitis and its Impact on Asthma, European Academy of Allergy and Clinical Immunology, and European Geriatric Medicine Society) Working Group has proposed some recommendations for older adults receiving the COVID-19 vaccines. Anaphylaxis to COVID-19 vaccines is extremely rare (from 1 per 100,000 to 5 per million injections). Symptoms are similar in younger and older adults but they tend to be more severe in the older patients. Adrenaline is the mainstay treatment and should be readily available. A flowchart is proposed to manage anaphylaxis in the older patients.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Anaphylaxis Type of study: Prognostic study Topics: Vaccines Limits: Aged / Humans / Male Language: English Journal: Allergy Year: 2021 Document Type: Article Affiliation country: All.14838

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Anaphylaxis Type of study: Prognostic study Topics: Vaccines Limits: Aged / Humans / Male Language: English Journal: Allergy Year: 2021 Document Type: Article Affiliation country: All.14838