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Novel Pulmonary Delivery of Antiviral Drugs for Treating COVID-19 in Patients with Parkinson's Disease.
Islam, Nazrul; Rahman, Shafiqur.
  • Islam N; Queensland University of Technology, Pharmacy Discipline, Faculty of Health, Brisbane, Queensland 4000, Australia.
  • Rahman S; Department of Pharmaceutical Sciences, South Dakota State University, Brookings, SD 57007, USA.
Curr Drug Deliv ; 19(3): 260-265, 2022.
Article in English | MEDLINE | ID: covidwho-1167204
Semantic information from SemMedBD (by NLM)
1. Parkinson Disease PROCESS_OF Patients
Subject
Parkinson Disease
Predicate
PROCESS_OF
Object
Patients
2. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
3. Disease PROCESS_OF Patients
Subject
Disease
Predicate
PROCESS_OF
Object
Patients
4. Pharmaceutical Preparations TREATS COVID-19
Subject
Pharmaceutical Preparations
Predicate
TREATS
Object
COVID-19
5. delivery method USES Antiviral Agents
Subject
delivery method
Predicate
USES
Object
Antiviral Agents
6. Antiviral Agents TREATS Complication
Subject
Antiviral Agents
Predicate
TREATS
Object
Complication
7. Complication PROCESS_OF Patients
Subject
Complication
Predicate
PROCESS_OF
Object
Patients
8. Parkinson Disease PROCESS_OF Patients
Subject
Parkinson Disease
Predicate
PROCESS_OF
Object
Patients
9. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
10. Disease PROCESS_OF Patients
Subject
Disease
Predicate
PROCESS_OF
Object
Patients
11. Pharmaceutical Preparations TREATS COVID-19
Subject
Pharmaceutical Preparations
Predicate
TREATS
Object
COVID-19
12. delivery method USES Antiviral Agents
Subject
delivery method
Predicate
USES
Object
Antiviral Agents
13. Antiviral Agents TREATS Complication
Subject
Antiviral Agents
Predicate
TREATS
Object
Complication
14. Complication PROCESS_OF Patients
Subject
Complication
Predicate
PROCESS_OF
Object
Patients
ABSTRACT
The COVID-19 pandemic has caused a significant burden on public health worldwide. Currently, there are limited medications for the treatment of COVID-19 in patients with Parkinson's disorder (PD). Several antiviral drugs and other pharmacotherapies have shown promising results and are used by various delivery methods. Among the antiviral drugs, amantadine alone was reported to provide therapeutic benefit against COVID-19 in patients with PD. Here, we propose novel strategies for pulmonary drug delivery technology of antiviral drug, amantadine. As such pulmonary delivery of this drug or in combination with the additional antiviral drugs could be a more effective strategy for the treatment of COVID-19-related complications in patients with PD. Furthermore, the important benefits and limitations of this novel delivery technology will be discussed.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Parkinson Disease / COVID-19 Limits: Humans Language: English Journal: Curr Drug Deliv Journal subject: Pharmacy / Pharmacology / Drug Therapy Year: 2022 Document Type: Article

Full text: Available Collection: International databases Database: MEDLINE Main subject: Parkinson Disease / COVID-19 Limits: Humans Language: English Journal: Curr Drug Deliv Journal subject: Pharmacy / Pharmacology / Drug Therapy Year: 2022 Document Type: Article