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Home Management of Patients with Moderate or Severe Respiratory Failure Secondary to COVID-19, Using Remote Monitoring and Oxygen with or without HFNC.
Annunziata, Anna; Coppola, Antonietta; Carannante, Novella; Simioli, Francesca; Lanza, Maurizia; Di Micco, Pierpaolo; Fiorentino, Giuseppe.
  • Annunziata A; Department of Respiratory Pathophysiology, Monaldi-Cotugno Hospital, 80131 Naples, Italy.
  • Coppola A; Department of Respiratory Pathophysiology, Monaldi-Cotugno Hospital, 80131 Naples, Italy.
  • Carannante N; First Division Infectious Disease, Cotugno Hospital, 80131 Naples, Italy.
  • Simioli F; Department of Respiratory Pathophysiology, Monaldi-Cotugno Hospital, 80131 Naples, Italy.
  • Lanza M; Department of Respiratory Pathophysiology, Monaldi-Cotugno Hospital, 80131 Naples, Italy.
  • Di Micco P; Department of Medicine, Fatebenefratelli Hospital of Naples, 80129 Naples, Italy.
  • Fiorentino G; Department of Respiratory Pathophysiology, Monaldi-Cotugno Hospital, 80131 Naples, Italy.
Pathogens ; 10(4)2021 Apr 01.
Article in English | MEDLINE | ID: covidwho-1167682
Semantic information from SemMedBD (by NLM)
1. COVID-19 CAUSES Respiratory Failure
Subject
COVID-19
Predicate
CAUSES
Object
Respiratory Failure
2. oxygen TREATS Patients
Subject
oxygen
Predicate
TREATS
Object
Patients
3. COVID-19 AFFECTS Patients
Subject
COVID-19
Predicate
AFFECTS
Object
Patients
4. Respiratory Failure PROCESS_OF Patients
Subject
Respiratory Failure
Predicate
PROCESS_OF
Object
Patients
5. oxygen ADMINISTERED_TO Patients
Subject
oxygen
Predicate
ADMINISTERED_TO
Object
Patients
6. Warburg Therapy USES Nasal Cannula
Subject
Warburg Therapy
Predicate
USES
Object
Nasal Cannula
7. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
8. Pulmonary failure PROCESS_OF Patients
Subject
Pulmonary failure
Predicate
PROCESS_OF
Object
Patients
9. Warburg Therapy TREATS At home
Subject
Warburg Therapy
Predicate
TREATS
Object
At home
10. COVID-19 CAUSES Respiratory Failure
Subject
COVID-19
Predicate
CAUSES
Object
Respiratory Failure
11. oxygen TREATS Patients
Subject
oxygen
Predicate
TREATS
Object
Patients
12. COVID-19 AFFECTS Patients
Subject
COVID-19
Predicate
AFFECTS
Object
Patients
13. Respiratory Failure PROCESS_OF Patients
Subject
Respiratory Failure
Predicate
PROCESS_OF
Object
Patients
14. oxygen ADMINISTERED_TO Patients
Subject
oxygen
Predicate
ADMINISTERED_TO
Object
Patients
15. Warburg Therapy USES Nasal Cannula
Subject
Warburg Therapy
Predicate
USES
Object
Nasal Cannula
16. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
17. Pulmonary failure PROCESS_OF Patients
Subject
Pulmonary failure
Predicate
PROCESS_OF
Object
Patients
18. Warburg Therapy TREATS At home
Subject
Warburg Therapy
Predicate
TREATS
Object
At home
ABSTRACT

BACKGROUND:

Home treatment of patients affected by COVID-19 is still a matter of daily debate. During the clinical evolution of the disease, there are high risks of lung failure, which requires oxygen therapy. Here, we report our clinical experience with at-home treatment using high-flow nasal cannula in non-hospitalised patients with confirmed COVID-19. PATIENTS AND

METHODS:

In this study, 18 patients with moderate-to-severe respiratory failure secondary to COVID-19 were monitored at home daily for temperature and SpO2 measurements. Other parameters such as saturation of peripheral oxygen (SpO2), SpO2/FiO2 (fraction of inspired oxygen), temperature, and lung performance were monitored periodically. Depending on oxygen requirements, the patients also received either standard oxygen via a face mask or, if higher FiO2 required, high-flow nasal cannula (HFNC).

RESULTS:

All 18 patients had favourable outcomes and recovered from COVID-19. No death was recorded in this group.

CONCLUSION:

Our clinical experience proves that high-flow nasal cannula oxygen therapy may be considered for at-home treatment of COVID-19 patients with moderate lung failure. This could be useful for further treatment during the pandemic and may also be considered in future epidemics.
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Full text: Available Collection: International databases Database: MEDLINE Language: English Year: 2021 Document Type: Article Affiliation country: Pathogens10040413

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Full text: Available Collection: International databases Database: MEDLINE Language: English Year: 2021 Document Type: Article Affiliation country: Pathogens10040413