Tobacco Smoking Increases the Lung Gene Expression of ACE2, the Receptor of SARS-CoV-2.

Cai, Guoshuai; Bossé, Yohan; Xiao, Feifei; Kheradmand, Farrah; Amos, Christopher I

Cai, Guoshuai; Bossé, Yohan; Xiao, Feifei; Kheradmand, Farrah; Amos, Christopher I.

Cai G; University of South CarolinaColumbia, South Carolina.
Bossé Y; Laval UniversityQuebec City, Quebec, Canada.
Xiao F; University of South CarolinaColumbia, South Carolina.
Kheradmand F; U.S. Department of Veterans AffairsHouston, Texasand.
Amos CI; Baylor College of MedicineHouston, Texas.

Am J Respir Crit Care Med ; 201(12): 1557-1559, 2020 06 15.

Article in English | MEDLINE | ID: covidwho-116825

Subject(s)

Furin/genetics; Lung/metabolism; Peptidyl-Dipeptidase A/genetics; Serine Endopeptidases/genetics; Tobacco Smoking/genetics; Angiotensin-Converting Enzyme 2; Asian People/genetics; Betacoronavirus/metabolism; COVID-19; Coronavirus Infections; Databases, Genetic; Ex-Smokers; Gene Expression Profiling; Humans; Non-Smokers; Pandemics; Peptidyl-Dipeptidase A/metabolism; Pneumonia, Viral; Pulmonary Disease, Chronic Obstructive/genetics; RNA-Seq; SARS-CoV-2; Smokers; Up-Regulation; White People/genetics

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Serine Endopeptidases / Peptidyl-Dipeptidase A / Furin / Tobacco Smoking / Lung Limits: Humans Language: English Journal: Am J Respir Crit Care Med Journal subject: Critical Care Year: 2020 Document Type: Article

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