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The impact of COVID-19 on short-term prognosis of ST-segment elevation myocardial infarction patients receiving primary percutaneous coronary intervention in Wuhan China.
Lu, Qing; Wang, Jiu-Long; Chen, Zhi-Nan; Fu, Wen-Bo; Liu, Hui-Jian; Ding, Shi-Fang.
  • Lu Q; Department of Cardiology, General Hospital of Central Theater Command, Wuhan, 430070 Hubei, P. R. China.
  • Wang JL; The First School of Clinical Medicine, Southern Medical University, Guangzhou, 510515 Guangdong, P. R. China.
  • Chen ZN; Department of Cardiology, General Hospital of Central Theater Command, Wuhan, 430070 Hubei, P. R. China.
  • Fu WB; Department of Cardiology, General Hospital of Central Theater Command, Wuhan, 430070 Hubei, P. R. China.
  • Liu HJ; Department of Cardiology, General Hospital of Central Theater Command, Wuhan, 430070 Hubei, P. R. China.
  • Ding SF; Department of Cardiology, General Hospital of Central Theater Command, Wuhan, 430070 Hubei, P. R. China.
Rev Cardiovasc Med ; 22(1): 247-256, 2021 03 30.
Article in English | MEDLINE | ID: covidwho-1168426
Semantic information from SemMedBD (by NLM)
1. ST segment elevation myocardial infarction PROCESS_OF Patients
Subject
ST segment elevation myocardial infarction
Predicate
PROCESS_OF
Object
Patients
2. Percutaneous Coronary Intervention ADMINISTERED_TO Patients
Subject
Percutaneous Coronary Intervention
Predicate
ADMINISTERED_TO
Object
Patients
3. CD69 protei AFFECTS C5203670
Subject
CD69 protei
Predicate
AFFECTS
Object
C5203670
4. Heart LOCATION_OF Adverse event
Subject
Heart
Predicate
LOCATION_OF
Object
Adverse event
5. Percutaneous Coronary Intervention TREATS ST segment elevation myocardial infarction
Subject
Percutaneous Coronary Intervention
Predicate
TREATS
Object
ST segment elevation myocardial infarction
6. Percutaneous Coronary Intervention TREATS Patients
Subject
Percutaneous Coronary Intervention
Predicate
TREATS
Object
Patients
7. ST segment elevation myocardial infarction COEXISTS_WITH COVID-19
Subject
ST segment elevation myocardial infarction
Predicate
COEXISTS_WITH
Object
COVID-19
8. ST segment elevation myocardial infarction PROCESS_OF Patients
Subject
ST segment elevation myocardial infarction
Predicate
PROCESS_OF
Object
Patients
9. Percutaneous Coronary Intervention ADMINISTERED_TO Patients
Subject
Percutaneous Coronary Intervention
Predicate
ADMINISTERED_TO
Object
Patients
10. CD69 protein, human|CD69 AFFECTS COVID-19
Subject
CD69 protein, human|CD69
Predicate
AFFECTS
Object
COVID-19
11. Heart LOCATION_OF Adverse event
Subject
Heart
Predicate
LOCATION_OF
Object
Adverse event
12. Percutaneous Coronary Intervention TREATS ST segment elevation myocardial infarction
Subject
Percutaneous Coronary Intervention
Predicate
TREATS
Object
ST segment elevation myocardial infarction
13. Percutaneous Coronary Intervention TREATS Patients
Subject
Percutaneous Coronary Intervention
Predicate
TREATS
Object
Patients
14. ST segment elevation myocardial infarction COEXISTS_WITH COVID-19
Subject
ST segment elevation myocardial infarction
Predicate
COEXISTS_WITH
Object
COVID-19
ABSTRACT
ST-segment elevation myocardial infarction (STEMI) is a common cardiovascular emergency for which timely reperfusion therapies are needed to minimize myocardial necrosis. The aim of this study was to investigate the impact of the COVID-19 pandemic and reorganization of chest pain centers (CPC) on the practice of primary percutaneous coronary intervention (PPCI) and prognosis of STEMI patients. This single-center retrospective survey included all patients with STEMI admitted to our CPC from January 22, 2020 to April 30, 2020 (during COVID-19 pandemic in Wuhan), compared with those admitted during the analogous period in 2019, in respect of important time points of PPCI and clinical outcomes of STEMI patients. In the present article, we observed a descending trend in STEMI hospitalization and a longer time from symptom onset to first medical contact during the COVID-19 pandemic as compared to the control period (4.35 h versus 2.58 h). With a median delay of 17 minutes in the door to balloon time (D2B), the proportion of in-hospital cardiogenic shock was significantly higher in the COVID-19 era group (47.6% versus 19.5%), and major adverse cardiac events (MACE) tend to increase in the 6-month follow-up period (14.3% versus 2.4%). Although the reorganization of CPC may prolong the D2B time, immediate revascularization of the infarct-related artery could be offered to most patients within 90 minutes upon arrival. PPCI remained the preferred treatment for patients with STEMI during COVID-19 pandemic in the context of timely implementation and appropriate protective measures.
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Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Percutaneous Coronary Intervention / ST Elevation Myocardial Infarction / COVID-19 / Myocardial Infarction Type of study: Diagnostic study / Observational study / Prognostic study / Risk factors Topics: Long Covid Limits: Humans Country/Region as subject: Asia Language: English Journal: Rev Cardiovasc Med Journal subject: Vascular Diseases / Cardiology Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Percutaneous Coronary Intervention / ST Elevation Myocardial Infarction / COVID-19 / Myocardial Infarction Type of study: Diagnostic study / Observational study / Prognostic study / Risk factors Topics: Long Covid Limits: Humans Country/Region as subject: Asia Language: English Journal: Rev Cardiovasc Med Journal subject: Vascular Diseases / Cardiology Year: 2021 Document Type: Article