Topical preparations to reduce SARS-CoV-2 aerosolization in head and neck mucosal surgery.
Head Neck
; 42(6): 1268-1272, 2020 06.
Article
in English
| MEDLINE | ID: covidwho-116903
ABSTRACT
AIM:
The COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has put health care workers at risk when exposed to aerosolized viral particles during upper airway mucosal surgery. The objective of this review was to discuss topical preparations that could be utilized preoperatively to help to decrease viral load and potentially reduce the risks of viral transmission.METHODS:
A PubMed/MEDLINE database review of articles was performed querying topical preparations with virucidal activity against coronaviruses.RESULTS:
Povidone-iodine (PVP-I) solutions ranging from 0.23% to 7% have been found to demonstrate highly effective virucidal activity against a broad range of viruses including several coronaviruses responsible for recent epidemics including SARS-CoV-1 and MERS-CoV.CONCLUSIONS:
While specific evidence regarding SARS-CoV-2 is lacking, PVP-I-based preparations have been successfully demonstrated to reduce viral loads of coronaviruses. They are relatively safe to use in the upper airway and may reduce risk of SARS-CoV-2 aerosolization during upper airway mucosal surgery.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Otolaryngology
/
Pneumonia, Viral
/
Infectious Disease Transmission, Patient-to-Professional
/
Coronavirus Infections
/
Pandemics
/
Betacoronavirus
/
Anti-Infective Agents, Local
Type of study:
Prognostic study
/
Reviews
Limits:
Humans
Language:
English
Journal:
Head Neck
Journal subject:
Neoplasms
Year:
2020
Document Type:
Article
Affiliation country:
Hed.26200
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