Bedside thromboelastography to rapidly assess the pharmacodynamic response of anticoagulants and aspirin in COVID-19: evidence of inadequate therapy in a predominantly minority population.

Gurbel, Paul A; Bliden, Kevin P; Rout, Amit; Rapista, Nicole; Walia, Naval; Chaudhary, Rahul; Ens, Gordon; Traianova, Malina; Barnes, Jaime S; Tantry, Udaya S

Bedside thromboelastography to rapidly assess the pharmacodynamic response of anticoagulants and aspirin in COVID-19: evidence of inadequate therapy in a predominantly minority population.

Gurbel, Paul A; Bliden, Kevin P; Rout, Amit; Rapista, Nicole; Walia, Naval; Chaudhary, Rahul; Ens, Gordon; Traianova, Malina; Barnes, Jaime S; Tantry, Udaya S.

Gurbel PA; Sinai Center for Thrombosis Research and Drug Development, Sinai Hospital of Baltimore, Lifebridge Health, Baltimore, MD, 21215, USA. pgurbel@lifebridgehealth.org.
Bliden KP; Sinai Center for Thrombosis Research and Drug Development, Sinai Hospital of Baltimore, Lifebridge Health, Baltimore, MD, 21215, USA.
Rout A; Sinai Center for Thrombosis Research and Drug Development, Sinai Hospital of Baltimore, Lifebridge Health, Baltimore, MD, 21215, USA.
Rapista N; Sinai Center for Thrombosis Research and Drug Development, Sinai Hospital of Baltimore, Lifebridge Health, Baltimore, MD, 21215, USA.
Walia N; Sinai Center for Thrombosis Research and Drug Development, Sinai Hospital of Baltimore, Lifebridge Health, Baltimore, MD, 21215, USA.
Chaudhary R; Division of Hospital Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Ens G; Inflammatory Markers Laboratory, Wichita, KS, USA.
Traianova M; CEDEX Laboratory, Nashua, NH, USA.
Barnes JS; Critical Care Medicine, Sinai Hospital and Northwest Hospital, Lifebridge Health, Baltimore, MD, USA.
Tantry US; Sinai Center for Thrombosis Research and Drug Development, Sinai Hospital of Baltimore, Lifebridge Health, Baltimore, MD, 21215, USA.

J Thromb Thrombolysis ; 51(4): 902-904, 2021 May.

Article in English | MEDLINE | ID: covidwho-1170900

Subject(s)

Anticoagulants; Aspirin; Biomarkers, Pharmacological/blood; COVID-19 Drug Treatment; COVID-19; Heparin; Point-of-Care Testing/statistics & numerical data; Thrombelastography/methods; Black or African American/statistics & numerical data; Anticoagulants/administration & dosage; Anticoagulants/pharmacokinetics; Aspirin/administration & dosage; Aspirin/pharmacokinetics; Biological Availability; COVID-19/blood; COVID-19/diagnosis; COVID-19/physiopathology; Female; Hemostasis/drug effects; Hemostasis/physiology; Heparin/administration & dosage; Heparin/pharmacokinetics; Humans; Male; Middle Aged; Platelet Aggregation Inhibitors/administration & dosage; Platelet Aggregation Inhibitors/pharmacokinetics; Platelet Function Tests/methods; Platelet Function Tests/statistics & numerical data; SARS-CoV-2; United States/epidemiology

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Thrombelastography / Heparin / Aspirin / Biomarkers, Pharmacological / Point-of-Care Testing / COVID-19 / COVID-19 Drug Treatment / Anticoagulants Type of study: Diagnostic study / Observational study Limits: Female / Humans / Male / Middle aged Country/Region as subject: North America Language: English Journal: J Thromb Thrombolysis Journal subject: Vascular Diseases Year: 2021 Document Type: Article Affiliation country: S11239-021-02435-1

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