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SARS-CoV-2 Not Detectable in Ocular Specimens of a Patient with a Past Infection.
Felfeli, Tina; Mazzulli, Tony; Clark, Shawn T; El-Defrawy, Sherif R; Chan, Clara C.
  • Felfeli T; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada.
  • Mazzulli T; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
  • Clark ST; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
  • El-Defrawy SR; Department of Microbiology, University Health Network/Mount Sinai Hospital, Toronto, ON, Canada.
  • Chan CC; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
Ocul Immunol Inflamm ; 29(4): 681-683, 2021 May 19.
Article in English | MEDLINE | ID: covidwho-1171738
ABSTRACT

Purpose:

To present a a case study that aims to investigate the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the ocular tissue samples of a patient previously infected with COVID-19 and determine its transmissibility.Study

Design:

Case Report

Results:

In this case study, SARS-CoV-2 was not detected in the vitreous and uveal tissue samples by RT-PCR for detection of three gene targets in a patient with a past COVID-19 infection 15 days prior to presention with a globe rupture.

Conclusions:

Our findings suggest that patients with long-term existence of SARS-CoV-2 at low detectable levels may not have active intraocular viral shedding. This is of particular importance as ophthalmic surgical procedures may potentiate virus spread from patients infected with SARS-CoV-2.
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Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Uvea / Vitreous Body / RNA, Viral / Eye Infections, Viral / SARS-CoV-2 / COVID-19 Type of study: Case report / Diagnostic study Topics: Long Covid Limits: Adult / Female / Humans Language: English Journal: Ocul Immunol Inflamm Journal subject: Allergy and Immunology / Ophthalmology Year: 2021 Document Type: Article Affiliation country: 09273948.2021.1894458

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Uvea / Vitreous Body / RNA, Viral / Eye Infections, Viral / SARS-CoV-2 / COVID-19 Type of study: Case report / Diagnostic study Topics: Long Covid Limits: Adult / Female / Humans Language: English Journal: Ocul Immunol Inflamm Journal subject: Allergy and Immunology / Ophthalmology Year: 2021 Document Type: Article Affiliation country: 09273948.2021.1894458