Your browser doesn't support javascript.
Early experience with universal SARS-CoV-2 testing in a New York-based reproductive endocrinology practice.
Gingold, Julian A; Galperin, Sharon; Fowler, Sabrina; Kappy, Michelle; Pollack, Staci; Singh, Manvinder; Lieman, Harry; Jindal, Sangita.
  • Gingold JA; Montefiore Medical Center,Institute for Reproductive Medicine and Health, Hartsdale, NY, USA.
  • Galperin S; Division of Reproductive Endocrinology and Infertility, Montefiore Medical Center, Bronx, NY, USA.
  • Fowler S; School of Medicine, Albert Einstein College of Medicine, Bronx, NY USA.
  • Kappy M; School of Medicine, Albert Einstein College of Medicine, Bronx, NY USA.
  • Pollack S; Department of OB/GYN and Women's Health, Montefiore Medical Center, Bronx, NY, USA.
  • Singh M; Montefiore Medical Center,Institute for Reproductive Medicine and Health, Hartsdale, NY, USA.
  • Lieman H; Division of Reproductive Endocrinology and Infertility, Montefiore Medical Center, Bronx, NY, USA.
  • Jindal S; Department of OB/GYN and Women's Health, Montefiore Medical Center, Bronx, NY, USA.
Syst Biol Reprod Med ; 67(2): 144-150, 2021 Apr.
Article in English | MEDLINE | ID: covidwho-1172615
ABSTRACT
The SARS-CoV-2 pandemic peak around March 2020 led to temporary closures of most fertility clinics. Many clinics reopened but required universal SARS-CoV-2 screening. However, the rate of positive results and the necessity for such testing is unknown. We report here on early results from asingle-center academic NewYork fertility practice utilizing universal SARS-CoV-2 screening. This mixed prospective retrospective cohort included 164 patients who underwent at least one SARS-CoV-2 screening test for fertility treatment between May and July2020. Patients completed 1 to 3 nasopharyngeal SARS-CoV-2 tests per cycle and remained symptom-free to continue fertility treatments. SARS-CoV-2 test results, past results, history of Covid-19 infection, and patient/cycle characteristics were recorded and tabulated through October2020. Outcomes included positive SARS-CoV-2 RNA tests, rate of prior Covid-19 infections, and clinical courses of patients testing positive. Patients underwent 263 cycles entailing 460 total SARS-CoV-2 screening tests. Fifteen patients reported astrong prior clinical history of Covid-19. Six patients experienced apositive SARS-CoV-2 test (2.3% of all cycles). Among 77 cycles (n = 58 patients) entailing one SARS-CoV-2 test, 2 cases (2.6%) were noted. Among 173 cycles (n = 121 patients) entailing two SARS-CoV-2 tests, 4 cycles (2.3%) were noted. Zero (0%) of 13 cycles (n = 13 patients) entailing 3 SARS-CoV-2 tests were positive. All patients were cleared to resume treatment within one month. Overall, anew asymptomatic infection was identified in 2 cycles (0.8%), while 4 of the 6 positive SARS-CoV-2 tests were among patients with aprior history of Covid-19. 3 of 4 also had adocumented prior positive RNA test. Our data suggest that universal SARS-CoV-2 screening among fertility patients is feasible, with an approximately 2% positive rate per cycle among the patients of this study. Most positive patients had aprior remote infection, but their infectiousness while being screened remains unclear.Abbreviations REI reproductive endocrinology and infertility; IUI intrauterine insemination; IVF in vitro fertilization; sono sonography; cryo cryopreservation; FET frozen embryo transfer.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Endocrinology / Fertility Clinics / COVID-19 Testing / COVID-19 Type of study: Cohort study / Diagnostic study / Observational study / Prognostic study Limits: Adult / Female / Humans Language: English Journal: Syst Biol Reprod Med Journal subject: Reproductive Medicine / Urology Year: 2021 Document Type: Article Affiliation country: 19396368.2021.1884317

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Endocrinology / Fertility Clinics / COVID-19 Testing / COVID-19 Type of study: Cohort study / Diagnostic study / Observational study / Prognostic study Limits: Adult / Female / Humans Language: English Journal: Syst Biol Reprod Med Journal subject: Reproductive Medicine / Urology Year: 2021 Document Type: Article Affiliation country: 19396368.2021.1884317