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History for some or lesson for all? A systematic review and meta-analysis on the immediate and long-term mental health impact of the 2002-2003 Severe Acute Respiratory Syndrome (SARS) outbreak.
Chau, Steven W H; Wong, Oscar W H; Ramakrishnan, Rema; Chan, Sandra S M; Wong, Evelyn K Y; Li, Pinky Y T; Raymont, Vanessa; Elliot, Kathryn; Rathod, Shanaya; Delanerolle, Gayathri; Phiri, Peter.
  • Chau SWH; Department of Psychiatry, The Chinese University of Hong Kong, Shatin, Hong Kong. stevenwaihochau@cuhk.edu.hk.
  • Wong OWH; Li Chiu Kong Family Sleep Assessment Unit, Department of Psychiatry, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong. stevenwaihochau@cuhk.edu.hk.
  • Ramakrishnan R; Department of Psychiatry, The Chinese University of Hong Kong, Shatin, Hong Kong.
  • Chan SSM; Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, UK.
  • Wong EKY; Department of Psychiatry, The Chinese University of Hong Kong, Shatin, Hong Kong.
  • Li PYT; Department of Psychiatry, North District Hospital, Sheung Shui, Hong Kong.
  • Raymont V; Department of Psychiatry, The Chinese University of Hong Kong, Shatin, Hong Kong.
  • Elliot K; Oxford Brain Health Clinical Trials Unit, Department of Psychiatry, University of Oxford, Oxford, UK.
  • Rathod S; Research & Development Department, Tom Rudd Unit, Clinical Trials Facility, Moorgreen Hospital, Southern Health NHS Foundation Trust, Southampton, SO30 3JB, UK.
  • Delanerolle G; School of Primary Care, Population Sciences and Medical Education, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Phiri P; Oxford Brain Health Clinical Trials Unit, Department of Psychiatry, University of Oxford, Oxford, UK.
BMC Public Health ; 21(1): 670, 2021 04 07.
Article in English | MEDLINE | ID: covidwho-1172830
ABSTRACT

BACKGROUND:

The aims of this systematic review and meta-analysis are to examine the prevalence of adverse mental health outcomes, both short-term and long-term, among SARS patients, healthcare workers and the general public of SARS-affected regions, and to examine the protective and risk factors associated with these mental health outcomes.

METHODS:

We conducted a systematic search of the literature using databases such as Medline, Pubmed, Embase, PsycInfo, Web of Science Core Collection, CNKI, the National Central Library Online Catalog and dissertation databases to identify studies in the English or Chinese language published between January 2003 to May 2020 which reported psychological distress and mental health morbidities among SARS patients, healthcare workers, and the general public in regions with major SARS outbreaks.

RESULTS:

The literature search yielded 6984 titles. Screening resulted in 80 papers for the review, 35 of which were included in the meta-analysis. The prevalence of post-recovery probable or clinician-diagnosed anxiety disorder, depressive disorder, and post-traumatic stress disorder (PTSD) among SARS survivors were 19, 20 and 28%, respectively. The prevalence of these outcomes among studies conducted within and beyond 6 months post-discharge was not significantly different. Certain aspects of mental health-related quality of life measures among SARS survivors remained impaired beyond 6 months post-discharge. The prevalence of probable depressive disorder and PTSD among healthcare workers post-SARS were 12 and 11%, respectively. The general public had increased anxiety levels during SARS, but whether there was a clinically significant population-wide mental health impact remained inconclusive. Narrative synthesis revealed occupational exposure to SARS patients and perceived stigmatisation to be risk factors for adverse mental health outcomes among healthcare workers, although causality could not be determined due to the limitations of the studies.

CONCLUSIONS:

The chronicity of psychiatric morbidities among SARS survivors should alert us to the potential long-term mental health complications of covid-19 patients. Healthcare workers working in high-risk venues should be given adequate mental health support. Stigmatisation against patients and healthcare workers should be explored and addressed. The significant risk of bias and high degree of heterogeneity among included studies limited the certainty of the body of evidence of the review.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Disease Outbreaks / Severe Acute Respiratory Syndrome / Mental Disorders Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study / Qualitative research / Reviews / Systematic review/Meta Analysis Topics: Long Covid Limits: Humans Language: English Journal: BMC Public Health Journal subject: Public Health Year: 2021 Document Type: Article Affiliation country: S12889-021-10701-3

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Disease Outbreaks / Severe Acute Respiratory Syndrome / Mental Disorders Type of study: Diagnostic study / Experimental Studies / Observational study / Prognostic study / Qualitative research / Reviews / Systematic review/Meta Analysis Topics: Long Covid Limits: Humans Language: English Journal: BMC Public Health Journal subject: Public Health Year: 2021 Document Type: Article Affiliation country: S12889-021-10701-3