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Use of Remdesivir in Myasthenia gravis and COVID-19.
Peters, Bradley J; Rabinstein, Alejandro A; DuBrock, Hilary M.
  • Peters BJ; Department of Pharmacy, Mayo Clinic, Rochester, Minnesota, USA.
  • Rabinstein AA; Division of Neurology, Mayo Clinic, Rochester, Minnesota, USA.
  • DuBrock HM; Division of Pulmonary & Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Pharmacotherapy ; 41(6): 546-550, 2021 06.
Article in English | MEDLINE | ID: covidwho-1173838
ABSTRACT
Myasthenia gravis and the associated pharmacologic management options could place patients at higher risk of contracting severe acute respiratory syndrome coronavirus 2 and exhibiting more severe manifestations of the novel coronavirus disease 2019 (COVID-19). Multiple agents have been studied for the management of the COVID-19, including remdesivir. To date, no published reports have evaluated the utilization of the antiviral remdesivir in patients with myasthenia gravis. We describe the first reported clinical course of three patients with myasthenia gravis who safely received remdesivir in combination with dexamethasone for the management of COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Adenosine Monophosphate / Alanine / COVID-19 / COVID-19 Drug Treatment / Myasthenia Gravis Type of study: Case report / Experimental Studies / Prognostic study Topics: Long Covid Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: English Journal: Pharmacotherapy Year: 2021 Document Type: Article Affiliation country: Phar.2524

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Antiviral Agents / Adenosine Monophosphate / Alanine / COVID-19 / COVID-19 Drug Treatment / Myasthenia Gravis Type of study: Case report / Experimental Studies / Prognostic study Topics: Long Covid Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: English Journal: Pharmacotherapy Year: 2021 Document Type: Article Affiliation country: Phar.2524