What would be the impact of COVID-19 on liver function of a patient with chronic hepatitis B? About a case and literature review.
Pan Afr Med J
; 38: 225, 2021.
Article
in English
| MEDLINE | ID: covidwho-1175756
ABSTRACT
Liver damage during COVID-19 disease has been described in numerous studies. Its mechanism is poorly understood. It is mainly reserved for severe forms and is manifested by abnormalities of the hepatic assessment and more particularly cytolysis. Particular attention must be paid to patients with chronic liver disease, both in terms of follow-up and treatment. We wanted to know the evolution of COVID-19 and its treatment, on the liver function of a 27-year-old patient followed for chronic non-cirrhotic hepatitis B at the Hassan II University Hospital in Fez. Our patient had stopped the antiviral B treatment and presented COVID-19 infection with minimal to moderate impairment. The initial evaluation showed cytolysis at 4 times upper limit of normal (ULN). Management consisted in the immediate resumption of Tenofovir in combination with hydroxychloroquine (HCQ) and azythromycin with good clinical and biological evolution.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Antiviral Agents
/
Hepatitis B, Chronic
/
COVID-19
Type of study:
Case report
/
Cohort study
/
Diagnostic study
/
Experimental Studies
/
Prognostic study
/
Reviews
Topics:
Long Covid
Limits:
Adult
/
Humans
/
Male
Country/Region as subject:
Africa
Language:
English
Journal:
Pan Afr Med J
Year:
2021
Document Type:
Article
Affiliation country:
Pamj.2021.38.225.28123
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