Rhino-orbital mucormycosis during steroid therapy in COVID-19 patients: A case report.
Eur J Ophthalmol
; 32(4): NP11-NP16, 2022 Jul.
Article
in English
| MEDLINE | ID: covidwho-1177699
ABSTRACT
PURPOSE:
To report two cases of COVID-19 under treatment with a corticosteroid; in one case rhino-orbitocerebral mucormycosis and in another one rhino-orbital mucormycosis developed. CASE PRESENTATION A 40-year old woman and a 54-year old man with severe COVID-19 underwent corticosteroid therapy for immune-related lung injuries. The first case presented with a bilateral visual loss and complete ophthalmoplegia of the right eye. The second case presented with vision loss, proptosis, orbital inflammation, and complete ophthalmoplegia on the left side. Histopathologic, nasal endoscopic examinations, and radiologic findings confirmed mucormycosis in both patients. The patients denied orbital exenteration and were managed with systemic amphotericin B and daily endoscopic sinus debridement and irrigation with diluted amphotericin B. Because of the intracranial space involvement, the first case died. The second case was successfully managed surgically and medically.CONCLUSION:
Rhino-orbital/cerebral mucormycosis may be developed in COVID-19 patients under treatment with corticosteroid, and requires prompt diagnosis and management.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Orbital Diseases
/
Eye Infections, Fungal
/
Ophthalmoplegia
/
Eye Diseases
/
COVID-19
/
Mucormycosis
Type of study:
Case report
/
Diagnostic study
Limits:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Language:
English
Journal:
Eur J Ophthalmol
Journal subject:
Ophthalmology
Year:
2022
Document Type:
Article
Affiliation country:
11206721211009450
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