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Vaccine development for emerging infectious diseases.
Excler, Jean-Louis; Saville, Melanie; Berkley, Seth; Kim, Jerome H.
  • Excler JL; International Vaccine Institute, Seoul, Republic of Korea. Jeanlouis.excler@ivi.int.
  • Saville M; Coalition for Epidemic Preparedness Innovations (CEPI), London, UK.
  • Berkley S; Gavi, the Vaccine Alliance, Geneva, Switzerland.
  • Kim JH; International Vaccine Institute, Seoul, Republic of Korea. Jerome.kim@ivi.int.
Nat Med ; 27(4): 591-600, 2021 04.
Article in English | MEDLINE | ID: covidwho-1180259
ABSTRACT
Examination of the vaccine strategies and technical platforms used for the COVID-19 pandemic in the context of those used for previous emerging and reemerging infectious diseases and pandemics may offer some mutually beneficial lessons. The unprecedented scale and rapidity of dissemination of recent emerging infectious diseases pose new challenges for vaccine developers, regulators, health authorities and political constituencies. Vaccine manufacturing and distribution are complex and challenging. While speed is essential, clinical development to emergency use authorization and licensure, pharmacovigilance of vaccine safety and surveillance of virus variants are also critical. Access to vaccines and vaccination needs to be prioritized in low- and middle-income countries. The combination of these factors will weigh heavily on the ultimate success of efforts to bring the current and any future emerging infectious disease pandemics to a close.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vaccines / Communicable Diseases, Emerging / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 Type of study: Observational study / Prognostic study Topics: Vaccines / Variants Limits: Humans Language: English Journal: Nat Med Journal subject: Molecular Biology / Medicine Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vaccines / Communicable Diseases, Emerging / COVID-19 Vaccines / SARS-CoV-2 / COVID-19 Type of study: Observational study / Prognostic study Topics: Vaccines / Variants Limits: Humans Language: English Journal: Nat Med Journal subject: Molecular Biology / Medicine Year: 2021 Document Type: Article