Your browser doesn't support javascript.
The use of whole blood capillary samples to measure 15 analytes for a home-collect biochemistry service during the SARS-CoV-2 pandemic: A proposed model from North West London Pathology.
Ansari, Saleem; Abdel-Malek, Mariana; Kenkre, Julia; Choudhury, Sirazum M; Barnes, Sophie; Misra, Shivani; Tan, Tricia; Cegla, Jaimini.
  • Ansari S; Blood Sciences, North West London Pathology, London, UK.
  • Abdel-Malek M; Blood Sciences, North West London Pathology, London, UK.
  • Kenkre J; Blood Sciences, North West London Pathology, London, UK.
  • Choudhury SM; Division of Diabetes, Endocrinology and Metabolism, Imperial College London, London, UK.
  • Barnes S; Blood Sciences, North West London Pathology, London, UK.
  • Misra S; Division of Diabetes, Endocrinology and Metabolism, Imperial College London, London, UK.
  • Tan T; Blood Sciences, North West London Pathology, London, UK.
  • Cegla J; Blood Sciences, North West London Pathology, London, UK.
Ann Clin Biochem ; 58(5): 411-421, 2021 09.
Article in English | MEDLINE | ID: covidwho-1181016
ABSTRACT

BACKGROUND:

The COVID-19 pandemic has drastically changed the delivery of secondary care services. Self-collection of capillary blood at home can facilitate the monitoring of patients with chronic disease to support virtual clinics while mitigating the risk of SARS-CoV-2 infection and transmission.

OBJECTIVE:

To investigate the comparability of whole blood capillary and plasma venous samples for 15 routinely used biochemical analytes and to develop and pilot a user-friendly home-collection kit to support virtual outpatient clinical services.

METHODS:

To investigate the comparability of whole blood capillary and plasma venous samples for 15 routinely requested biochemical analytes, simultaneous samples of venous and capillary blood were collected in EDTA and lithium-heparin plasma separation tubes that were of 4-6 mL and 400-600 µL draw volume, respectively. Venous samples were analysed within 4 h of collection while capillary samples were kept at ambient temperature for three days until centrifugation and analysis. Analyte results that were comparable between the matrices were then piloted in a feasibility study in three outpatient clinical services.

RESULTS:

HbA1c, lipid profile and liver function tests were considered comparable and piloted in the patient feasibility study. The home-collect kit demonstrated good patient usability.

CONCLUSION:

Home collection of capillary blood could be a clinically-useful tool to deliver virtual care to patients with chronic disease.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Blood Chemical Analysis / Blood Specimen Collection / Pandemics / SARS-CoV-2 / COVID-19 Type of study: Observational study / Prognostic study / Randomized controlled trials Limits: Adult / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Journal: Ann Clin Biochem Year: 2021 Document Type: Article Affiliation country: 00045632211004995

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Blood Chemical Analysis / Blood Specimen Collection / Pandemics / SARS-CoV-2 / COVID-19 Type of study: Observational study / Prognostic study / Randomized controlled trials Limits: Adult / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Journal: Ann Clin Biochem Year: 2021 Document Type: Article Affiliation country: 00045632211004995