Aptamers: The Powerful Molecular Tools for Virus Detection.
Chem Asian J
; 16(11): 1298-1306, 2021 Jun 01.
Article
in English
| MEDLINE | ID: covidwho-1182102
ABSTRACT
Aptamers are short single-stranded DNA or RNA oligonucleotides selected by the technique of systematic evolution of ligands by exponential enrichment (SELEX). Aptamers have been demonstrated to bind various targets from small-molecule to cells or even tissues in the way of antibodies. Thus, they are called chemical antibodies. We summarize and evaluate recent developments in aptamer-based sensors (for short aptasensors) for virus detection in this review. These aptasensors are mainly classified into optical and electronic aptasensors based on the type of transducer. Nowadays, the smartphone has become the most widely used mobile device with billions of users worldwide. Considering the ongoing COVID-19 outbreak, smartphone-based aptasensors for a portable and point-of-care test (POCT) of COVID-19 detection will be of great importance in the future.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Viral Proteins
/
Viruses
/
Biosensing Techniques
/
Aptamers, Nucleotide
Type of study:
Experimental Studies
/
Systematic review/Meta Analysis
Limits:
Humans
Language:
English
Journal:
Chem Asian J
Year:
2021
Document Type:
Article
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