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Physical inactivity is associated with a higher risk for severe COVID-19 outcomes: a study in 48 440 adult patients.
Sallis, Robert; Young, Deborah Rohm; Tartof, Sara Y; Sallis, James F; Sall, Jeevan; Li, Qiaowu; Smith, Gary N; Cohen, Deborah A.
  • Sallis R; Department of Family and Sports Medicine, Kaiser Permanente Medical Center, Fontana, California, USA Robert.E.Sallis@kp.org.
  • Young DR; Research and Evaluation, Southern California Permanente Medical Group, Pasadena, California, USA.
  • Tartof SY; Research and Evaluation, Southern California Permanente Medical Group, Pasadena, California, USA.
  • Sallis JF; University of California San Diego, La Jolla, California, USA.
  • Sall J; Department of Family and Sports Medicine, Kaiser Permanente Medical Center, Fontana, California, USA.
  • Li Q; Research and Evaluation, Southern California Permanente Medical Group, Pasadena, California, USA.
  • Smith GN; Economics Department, Pomona College, Claremont, California, USA.
  • Cohen DA; Research and Evaluation, Southern California Permanente Medical Group, Pasadena, California, USA.
Br J Sports Med ; 55(19): 1099-1105, 2021 Oct.
Article in English | MEDLINE | ID: covidwho-1183311
Semantic information from SemMedBD (by NLM)
1. American College of Cardiology/American Heart Association Lesion Complexity Score C PROCESS_OF Patients
Subject
American College of Cardiology/American Heart Association Lesion Complexity Score C
Predicate
PROCESS_OF
Object
Patients
2. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
3. Diagnosis PRECEDES Hospitalization
Subject
Diagnosis
Predicate
PRECEDES
Object
Hospitalization
4. COVID-19 CAUSES Cessation of life
Subject
COVID-19
Predicate
CAUSES
Object
Cessation of life
5. Infected PROCESS_OF Adult
Subject
Infected
Predicate
PROCESS_OF
Object
Adult
6. American College of Cardiology/American Heart Association Lesion Complexity Score C PROCESS_OF Patients
Subject
American College of Cardiology/American Heart Association Lesion Complexity Score C
Predicate
PROCESS_OF
Object
Patients
7. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
8. Diagnosis PRECEDES Hospitalization
Subject
Diagnosis
Predicate
PRECEDES
Object
Hospitalization
9. COVID-19 CAUSES Cessation of life
Subject
COVID-19
Predicate
CAUSES
Object
Cessation of life
10. Infected PROCESS_OF Adult
Subject
Infected
Predicate
PROCESS_OF
Object
Adult
ABSTRACT

OBJECTIVES:

To compare hospitalisation rates, intensive care unit (ICU) admissions and mortality for patients with COVID-19 who were consistently inactive, doing some activity or consistently meeting physical activity guidelines.

METHODS:

We identified 48 440 adult patients with a COVID-19 diagnosis from 1 January 2020 to 21 October 2020, with at least three exercise vital sign measurements from 19 March 2018 to 18 March 2020. We linked each patient's self-reported physical activity category (consistently inactive=0-10 min/week, some activity=11-149 min/week, consistently meeting guidelines=150+ min/week) to the risk of hospitalisation, ICU admission and death after COVID-19 diagnosis. We conducted multivariable logistic regression controlling for demographics and known risk factors to assess whether inactivity was associated with COVID-19 outcomes.

RESULTS:

Patients with COVID-19 who were consistently inactive had a greater risk of hospitalisation (OR 2.26; 95% CI 1.81 to 2.83), admission to the ICU (OR 1.73; 95% CI 1.18 to 2.55) and death (OR 2.49; 95% CI 1.33 to 4.67) due to COVID-19 than patients who were consistently meeting physical activity guidelines. Patients who were consistently inactive also had a greater risk of hospitalisation (OR 1.20; 95% CI 1.10 to 1.32), admission to the ICU (OR 1.10; 95% CI 0.93 to 1.29) and death (OR 1.32; 95% CI 1.09 to 1.60) due to COVID-19 than patients who were doing some physical activity.

CONCLUSIONS:

Consistently meeting physical activity guidelines was strongly associated with a reduced risk for severe COVID-19 outcomes among infected adults. We recommend efforts to promote physical activity be prioritised by public health agencies and incorporated into routine medical care.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Sedentary Behavior / COVID-19 / Hospitalization / Intensive Care Units Type of study: Etiology study / Clinical Practice Guide / Prognostic study / Risk factors Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: English Journal: Br J Sports Med Year: 2021 Document Type: Article Affiliation country: Bjsports-2021-104080

Full text: Available Collection: International databases Database: MEDLINE Main subject: Sedentary Behavior / COVID-19 / Hospitalization / Intensive Care Units Type of study: Etiology study / Clinical Practice Guide / Prognostic study / Risk factors Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: English Journal: Br J Sports Med Year: 2021 Document Type: Article Affiliation country: Bjsports-2021-104080