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COVID-19 and Cardiovascular Disease: From Bench to Bedside.
Chung, Mina K; Zidar, David A; Bristow, Michael R; Cameron, Scott J; Chan, Timothy; Harding, Clifford V; Kwon, Deborah H; Singh, Tamanna; Tilton, John C; Tsai, Emily J; Tucker, Nathan R; Barnard, John; Loscalzo, Joseph.
  • Chung MK; Cleveland Clinic (M.K.C., S.J.C., T.C., D.H.K., T.S., J.B.), OH.
  • Zidar DA; Cleveland Clinic Lerner College of Medicine (M.K.C., S.J.C., T.C., D.H.K., T.S., J.B.), OH.
  • Bristow MR; Case Western Reserve University School of Medicine (M.K.C., D.A.Z., S.J.C., T.C., C.V.H., D.H.K., T.S., J.C.T.), OH.
  • Cameron SJ; Case Western Reserve University School of Medicine (M.K.C., D.A.Z., S.J.C., T.C., C.V.H., D.H.K., T.S., J.C.T.), OH.
  • Chan T; Louis Stokes Cleveland Veterans Affairs Medical Center, OH (D.A.Z.).
  • Harding CV; University of Colorado Anschutz Medical Center, Aurora (M.R.B.).
  • Kwon DH; Cleveland Clinic (M.K.C., S.J.C., T.C., D.H.K., T.S., J.B.), OH.
  • Singh T; Cleveland Clinic Lerner College of Medicine (M.K.C., S.J.C., T.C., D.H.K., T.S., J.B.), OH.
  • Tilton JC; Case Western Reserve University School of Medicine (M.K.C., D.A.Z., S.J.C., T.C., C.V.H., D.H.K., T.S., J.C.T.), OH.
  • Tsai EJ; Cleveland Clinic (M.K.C., S.J.C., T.C., D.H.K., T.S., J.B.), OH.
  • Tucker NR; Cleveland Clinic Lerner College of Medicine (M.K.C., S.J.C., T.C., D.H.K., T.S., J.B.), OH.
  • Barnard J; Case Western Reserve University School of Medicine (M.K.C., D.A.Z., S.J.C., T.C., C.V.H., D.H.K., T.S., J.C.T.), OH.
  • Loscalzo J; Case Western Reserve University School of Medicine (M.K.C., D.A.Z., S.J.C., T.C., C.V.H., D.H.K., T.S., J.C.T.), OH.
Circ Res ; 128(8): 1214-1236, 2021 04 16.
Article in English | MEDLINE | ID: covidwho-1186415
ABSTRACT
A pandemic of historic impact, coronavirus disease 2019 (COVID-19) has potential consequences on the cardiovascular health of millions of people who survive infection worldwide. Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), the etiologic agent of COVID-19, can infect the heart, vascular tissues, and circulating cells through ACE2 (angiotensin-converting enzyme 2), the host cell receptor for the viral spike protein. Acute cardiac injury is a common extrapulmonary manifestation of COVID-19 with potential chronic consequences. This update provides a review of the clinical manifestations of cardiovascular involvement, potential direct SARS-CoV-2 and indirect immune response mechanisms impacting the cardiovascular system, and implications for the management of patients after recovery from acute COVID-19 infection.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Cardiovascular Diseases / Myocytes, Cardiac / Virus Internalization / Angiotensin-Converting Enzyme 2 / SARS-CoV-2 / COVID-19 Type of study: Etiology study / Observational study / Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: Circ Res Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Cardiovascular Diseases / Myocytes, Cardiac / Virus Internalization / Angiotensin-Converting Enzyme 2 / SARS-CoV-2 / COVID-19 Type of study: Etiology study / Observational study / Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: Circ Res Year: 2021 Document Type: Article