Scalable nanoprecipitation of niclosamide and in vivo demonstration of long-acting delivery after intramuscular injection.
Nanoscale
; 13(13): 6410-6416, 2021 Apr 07.
Article
in English
| MEDLINE | ID: covidwho-1189295
ABSTRACT
The control of COVID-19 across the world requires the formation of a range of interventions including vaccines to elicit an immune response and immunomodulatory or antiviral therapeutics. Here, we demonstrate the nanoparticle formulation of a highly insoluble drug compound, niclosamide, with known anti SARS-CoV-2 activity as a cheap and scalable long-acting injectable antiviral candidate.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Antiviral Agents
/
SARS-CoV-2
/
COVID-19 Drug Treatment
/
Niclosamide
Topics:
Vaccines
Limits:
Humans
Language:
English
Journal:
Nanoscale
Year:
2021
Document Type:
Article
Affiliation country:
D1nr00309g
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