Your browser doesn't support javascript.
Is Re-introducing Major Open and Minimally Invasive Surgery during COVID-19 Safe for Patients and Healthcare Workers? An International, Multi-centre Cohort Study in the Field of Oesophago-gastric Surgery.
Alasmar, Mohamed; Kausar, Afsana; Borgstein, Alexander Berend-Jan; Moons, Johnny; Doran, Sophie; de Pascale, Stefano; Restrepo, Rafael; Verrengia, Apollonia; Alloggio, Mariella; Delgado, Ana Moro; Kumar, Sacheen; Del Val, Ismael Díez; Giocapuzzi, Simone; Baiocchi, Gian Luca; de Vega Irañeta, Marta; Salcedo, Gabriel; Vorwald, Peter; Fumagalli Romario, Uberto; Nafteux, Philippe; Gisbertz, Suzanne; Chaudry, Mohammed Asif; Alkhaffaf, Bilal.
  • Alasmar M; Department of Oesophago-Gastric Surgery, Salford Royal NHS Foundation Trust, Salford Royal Hospital, Manchester, UK.
  • Kausar A; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
  • Borgstein AB; Department of Oesophago-Gastric Surgery, Salford Royal NHS Foundation Trust, Salford Royal Hospital, Manchester, UK.
  • Moons J; Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
  • Doran S; Department of Thoracic Surgery, University Hospitals Leuven, Leuven, Belgium.
  • de Pascale S; Department of Academic Surgery, Royal Marsden NHS Foundation Trust, London, UK.
  • Restrepo R; Istituto Europeo di Oncologia - IRCCS, Milan, Italy.
  • Verrengia A; Hospital Universitario Fundación Jiménez Diaz, Madrid, Spain.
  • Alloggio M; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
  • Delgado AM; University of Verona, Verona, Italy.
  • Kumar S; Basurto University Hospital, Bilbao, Spain.
  • Del Val ID; Department of Academic Surgery, Royal Marsden NHS Foundation Trust, London, UK.
  • Giocapuzzi S; Basurto University Hospital, Bilbao, Spain.
  • Baiocchi GL; University of Verona, Verona, Italy.
  • de Vega Irañeta M; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
  • Salcedo G; Hospital Universitario Fuenlabrada, Madrid, Spain.
  • Vorwald P; Hospital Universitario Fundación Jiménez Diaz, Madrid, Spain.
  • Fumagalli Romario U; Hospital Universitario Fundación Jiménez Diaz, Madrid, Spain.
  • Nafteux P; Istituto Europeo di Oncologia - IRCCS, Milan, Italy.
  • Gisbertz S; Department of Thoracic Surgery, University Hospitals Leuven, Leuven, Belgium.
  • Chaudry MA; Department of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
  • Alkhaffaf B; Department of Academic Surgery, Royal Marsden NHS Foundation Trust, London, UK.
Ann Surg Oncol ; 28(9): 4816-4826, 2021 Sep.
Article in English | MEDLINE | ID: covidwho-1190139
Semantic information from SemMedBD (by NLM)
1. Mullerian duct inhibiting substance|AMH TREATS Patients
Subject
Mullerian duct inhibiting substance|AMH
Predicate
TREATS
Object
Patients
2. COVID-19 NEG_PROCESS_OF Patients
Subject
COVID-19
Predicate
NEG_PROCESS_OF
Object
Patients
3. COVID-19 PROCESS_OF Health Personnel
Subject
COVID-19
Predicate
PROCESS_OF
Object
Health Personnel
4. Mullerian duct inhibiting substance|AMH TREATS Patients
Subject
Mullerian duct inhibiting substance|AMH
Predicate
TREATS
Object
Patients
5. COVID-19 NEG_PROCESS_OF Patients
Subject
COVID-19
Predicate
NEG_PROCESS_OF
Object
Patients
6. COVID-19 PROCESS_OF Health Personnel
Subject
COVID-19
Predicate
PROCESS_OF
Object
Health Personnel
ABSTRACT

INTRODUCTION:

The COVID-19 pandemic has resulted in unparalleled changes to patient care, including the suspension of cancer surgery. Concerns regarding COVID-19-related risks to patients and healthcare workers with the re-introduction of major complex minimally invasive and open surgery have been raised. This study examines the COVID-19 related risks to patients and healthcare workers following the re-introduction of major oesophago-gastric (EG) surgery. PATIENTS AND

METHODS:

This was an international, multi-centre, observational study of consecutive patients treated by open and minimally invasive oesophagectomy and gastrectomy for malignant or benign disease. Patients were recruited from nine European centres serving regions with a high population incidence of COVID-19 between 1 May and 1 July 2020. The primary endpoint was 30-day COVID-19-related mortality. All staff involved in the operative care of patients were invited to complete a health-related survey to assess the incidence of COVID-19 in this group.

RESULTS:

In total, 158 patients were included in the study (71 oesophagectomy, 82 gastrectomy). Overall, 87 patients (57%) underwent MIS (59 oesophagectomy, 28 gastrectomy). A total of 403 staff were eligible for inclusion, of whom 313 (78%) completed the health survey. Approaches to mitigate against the risks of COVID-19 for patients and staff varied amongst centres. No patients developed COVID-19 in the post-operative period. Two healthcare workers developed self-limiting COVID-19.

CONCLUSIONS:

Precautions to minimise the risk of COVID-19 infection have enabled the safe re-introduction of minimally invasive and open EG surgery for both patients and staff. Further studies are necessary to determine the minimum requirements for mitigations against COVID-19.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pandemics / COVID-19 Type of study: Controlled clinical trial / Etiology study / Observational study / Risk factors Limits: Humans Language: English Journal: Ann Surg Oncol Journal subject: Neoplasms Year: 2021 Document Type: Article Affiliation country: S10434-021-09885-0

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pandemics / COVID-19 Type of study: Controlled clinical trial / Etiology study / Observational study / Risk factors Limits: Humans Language: English Journal: Ann Surg Oncol Journal subject: Neoplasms Year: 2021 Document Type: Article Affiliation country: S10434-021-09885-0