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The associations of life quality, depression, and cognitive impairment with mortality in older adults with COVID-19: a prospective, observational study.
Bayrak, Muharrem; Çadirci, Kenan.
  • Bayrak M; Department of Internal Medicine, Erzurum Regional Training and Research Hospital, Health Sciences University, Erzurum, Turkey.
  • Çadirci K; Department of Internal Medicine, Erzurum Regional Training and Research Hospital, Health Sciences University, Erzurum, Turkey.
Acta Clin Belg ; : 1-8, 2021 Apr 17.
Article in English | MEDLINE | ID: covidwho-1191081
Semantic information from SemMedBD (by NLM)
1. COVID-19 PROCESS_OF Elderly (population group)
Subject
COVID-19
Predicate
PROCESS_OF
Object
Elderly (population group)
2. Depressive disorder PROCESS_OF Elderly (population group)
Subject
Depressive disorder
Predicate
PROCESS_OF
Object
Elderly (population group)
3. Impaired cognition PROCESS_OF Elderly (population group)
Subject
Impaired cognition
Predicate
PROCESS_OF
Object
Elderly (population group)
4. Dementia COEXISTS_WITH Depressive disorder
Subject
Dementia
Predicate
COEXISTS_WITH
Object
Depressive disorder
5. hospital patient care ADMINISTERED_TO Patients
Subject
hospital patient care
Predicate
ADMINISTERED_TO
Object
Patients
6. hospital patient care TREATS COVID-19
Subject
hospital patient care
Predicate
TREATS
Object
COVID-19
7. Polypharmacy ADMINISTERED_TO Patients
Subject
Polypharmacy
Predicate
ADMINISTERED_TO
Object
Patients
8. Comorbidity PROCESS_OF Patients
Subject
Comorbidity
Predicate
PROCESS_OF
Object
Patients
9. At risk for falls PROCESS_OF Elderly (population group)
Subject
At risk for falls
Predicate
PROCESS_OF
Object
Elderly (population group)
10. COVID-19 PROCESS_OF Elderly (population group)
Subject
COVID-19
Predicate
PROCESS_OF
Object
Elderly (population group)
11. Depressive disorder PROCESS_OF Elderly (population group)
Subject
Depressive disorder
Predicate
PROCESS_OF
Object
Elderly (population group)
12. Impaired cognition PROCESS_OF Elderly (population group)
Subject
Impaired cognition
Predicate
PROCESS_OF
Object
Elderly (population group)
13. Dementia COEXISTS_WITH Depressive disorder
Subject
Dementia
Predicate
COEXISTS_WITH
Object
Depressive disorder
14. hospital patient care ADMINISTERED_TO Patients
Subject
hospital patient care
Predicate
ADMINISTERED_TO
Object
Patients
15. hospital patient care TREATS COVID-19
Subject
hospital patient care
Predicate
TREATS
Object
COVID-19
16. Polypharmacy ADMINISTERED_TO Patients
Subject
Polypharmacy
Predicate
ADMINISTERED_TO
Object
Patients
17. Comorbidity PROCESS_OF Patients
Subject
Comorbidity
Predicate
PROCESS_OF
Object
Patients
18. At risk for falls PROCESS_OF Elderly (population group)
Subject
At risk for falls
Predicate
PROCESS_OF
Object
Elderly (population group)
ABSTRACT

AIM:

Associations of depression, dementia, and poor life quality with mortality of COVID-19have not been studied yet. We aimed to identify the risk factors for mortality and analyze the associations with patients' physiological and mental well-being, as reflected by comorbidities, life quality, depression, and cognitive impairment.

METHODS:

Older patients receiving inpatient hospital care for COVID-19 were included.Demographic data, medical history, symptoms at admission, laboratory findings, and treatment outcomes were recorded.

RESULTS:

There were 122 patients with a median age of 73.0 years. The mortality rate was 9.0% (n = 11 patients). Patients with mortality were significantly active smokers, obese, and having comorbidities using polypharmacy. Weight loss ≥of 10% during hospitalization was significantly associated with mortality.Poor life quality and a higher risk of depression, cognitive impairment, and falling were more frequently seen in non-survived patients. (p < 0.05). High ferritin was the only independent risk factor for mortality (OR = 15.61, 95% CI1.08-226.09, p = 0.044).

CONCLUSION:

The presence of comorbidities, depression, cognitive impairment, higher falling risk, and poor life quality were significantly associated with higher mortality rates in older adults with COVID-19. High ferritin level was an independent risk factor for mortality.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study / Prognostic study / Risk factors Language: English Journal: Acta Clin Belg Year: 2021 Document Type: Article Affiliation country: 17843286.2021.1916687

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Observational study / Prognostic study / Risk factors Language: English Journal: Acta Clin Belg Year: 2021 Document Type: Article Affiliation country: 17843286.2021.1916687