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Positive end-expiratory pressure in COVID-19-related ARDS: Do not forget the airway closure.
Brault, Clément; Zerbib, Yoann; Kontar, Loay; Carpentier, Mathieu; Maizel, Julien; Slama, Michel.
  • Brault C; Intensive Care Department, CHU Amiens-Picardie, 1 rue du Professeur Christian Cabrol, F-80000 Amiens, France. Electronic address: brault.clement@chu-amiens.fr.
  • Zerbib Y; Intensive Care Department, CHU Amiens-Picardie, 1 rue du Professeur Christian Cabrol, F-80000 Amiens, France.
  • Kontar L; Intensive Care Department, CHU Amiens-Picardie, 1 rue du Professeur Christian Cabrol, F-80000 Amiens, France.
  • Carpentier M; Intensive Care Department, CHU Amiens-Picardie, 1 rue du Professeur Christian Cabrol, F-80000 Amiens, France.
  • Maizel J; Intensive Care Department, CHU Amiens-Picardie, 1 rue du Professeur Christian Cabrol, F-80000 Amiens, France.
  • Slama M; Intensive Care Department, CHU Amiens-Picardie, 1 rue du Professeur Christian Cabrol, F-80000 Amiens, France.
J Crit Care ; 64: 141-143, 2021 08.
Article in English | MEDLINE | ID: covidwho-1193376
ABSTRACT
Airway closure is a physiological phenomenon in which the distal airways are obstructed when the airway pressure drops below the airway opening pressure. We assessed this phenomenon in 27 patients with coronavirus disease 2019-related acute respiratory distress syndrome. Twelve (44%) patients had an airway opening pressure above 5 cmH2O. The median airway opening pressure was 8 cmH2O (interquartile range, 7-10), with a maximum value of 17 cmH2O. Three patients had a baseline positive end-expiratory pressure lower than the airway opening pressure.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Respiratory Distress Syndrome / Positive-Pressure Respiration / SARS-CoV-2 / COVID-19 Type of study: Observational study Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Journal: J Crit Care Journal subject: Critical Care Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Respiratory Distress Syndrome / Positive-Pressure Respiration / SARS-CoV-2 / COVID-19 Type of study: Observational study Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Journal: J Crit Care Journal subject: Critical Care Year: 2021 Document Type: Article